The outcome of IHE initiatives is providing better information for developing health policy and best medical practices. IHE disseminates information in many ways. In addition to publications in peer-reviewed journals, IHE produces books and a variety of reports synthesizing information in a particular field.
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23 November 2018 | 30 November 2018 Calgary, Alberta | Edmonton, Alberta On November 23rd in Calgary and November 30th in Edmonton, the Institute of Health Economics (IHE) hosted an educational workshop designed to support both early and late stage organizations in developing an understanding of when, where, and how health economics can be used to strengthen product and business…
This report provides a summary of a real-world evidence (RWE) design sprint workshop that took place on October 21, 2018 in Toronto, Ontario. The workshop was developed and delivered as a joint partnership between the Canadian Agency for Drugs and Technologies in Health (CADTH); Canadian Association for Population Therapeutics (CAPT), Health Canada, and the Institute of Health…
| Dat Tran, Robert Welsh, Arto Ohinmaa, Thanh Nguyen, Padma Kaul
Little is known about the resource use and cost burden of acute myocardial infarction (AMI) beyond the index event. We examined resource use and care costs during the first and each subsequent year, among patients with incident AMI.
This environmental scan describes existing initiatives that aim to accelerate the diagnostic phase of cancer care in Alberta, Canada, and internationally. Specifically, it describes their development and implementation, structure and functioning, intended outcomes and effectiveness, costs and cost savings, and enablers and barriers.
21 October 2018 Toronto, Ontario On October 21, 2018, Health Canada, the Canadian Agency for Drugs and Technologies in Health (CADTH), the Institute of Health Economics (IHE), and the Canadian Association for Population Therapeutics (CAPT) collaborated on Defining Decision-Grade Real-World Evidence and its Role in the Canadian Context: A Design Sprint. Held as a satellite to the…
24 September 2018 Calgary, Alberta On September 24th, 2018 the Institute Health Economics (IHE) presented a roundtable at the BIO Alberta AGM and Conference. This Roundtable provided an overview of the IHE's education series for Alberta SMEs and ecosystem partners, and enabled participants to help define the content of the series so it would be most valuable to them. Beginning…
14 September 2018 Edmonton, Alberta The Institute of Health Economics and The Network of Alberta Health Economists were pleased to present "Reflections on Balancing Academic and Policy Work," a mentorship and networking event for early career health economists (7 years or less from completion of PhD studies), with renown Health Economist, Dr. Karl Claxton, Professor of Economics,…
19 September 2018Edmonton, Alberta Realistic Medicine - Trailer Realistic Medicine is the 18th IHE Innovation Forum, a semi-annual event bringing together senior public- and private-sector experts and decision-makers to address health care policy issues. Our 18th IHE Innovation Forum Keynote Speaker is Dr. Catherine Calderwood, Chief Medical Officer for the Scottish Government.…
4 – 6 November 2014 Edmonton, Alberta The Institute of Health Economics, in collaboration with the Government of Alberta and with support from Alberta Health Services (AHS), hosted the Consensus Development Conference on Improving Mental Health Transitions in Edmonton, Alberta, from November 4 – 6, 2014. Download Consensus Statement | Télécharger la déclaration de consensus The…
| S.P. Bisch, T. Wells, L. Gramlich, P. Faris, X. Wang, Dat Tran, Thanh Nguyen, S. Glaze, P. Chu, P. Ghatage, J. Nation, V. Capstick, H. Steed, J. Sabourin, G. Nelson
The Institute of Health Economics has contributed to a study published in the Journal Gynecologic Oncology. The study described the effects of Enhanced Recovery After Surgery (ERAS) guideline implementation in gynecologic oncology on length of stay, patient outcomes, and economic impact in Alberta. The study compared pre-and post-guideline implementation outcomes at two centers…
This study originated from discussions on how to translate research findings into conclusions regarding safety and effectiveness in systematic reviews responding to requests from a provincial mechanism for introducing and diffusing publicly funded healthcare technologies. Its objective is to identify prominent and reliable evidence grading systems used in health technology assessment…
This clinical practice guideline was produced as part of the Prairie Collaborative Immune Globulin (IG) Utilization Management Framework project, which was initiated to establish criteria for IG therapy as a means to increase accountability for the quality, safety, and sustainability of the blood supply system, and to demonstrate stewardship for the use of public funds. This project…
This background document outlines the methods used to develop the Criteria for the Clinical Use of Immune Globulin, which was produced as part of the Prairie Collaborative Immune Globulin Utilization Management Framework project. The Prairie Collaborative Immune Globulin (IG) Utilization Management Framework project was initiated to establish criteria for IG therapy as a means…
3 June 2018 Vancouver, British Columbia On June 3rd, as part of the 2018 Health Technology Assessment International (HTAi) Annual Conference in Vancouver, the Institute of Health Economics (IHE) led a panel presentation on facilitators, innovators, and innovations in chronic obstructive pulmonary disease (COPD) care in Canada. The panel, Facilitating Adoption of Innovative…
| Jasmine Brown, Roger Bland, Egon Jonsson, Andrew Greenshaw
Objective: Fetal alcohol spectrum disorder (FASD) is a medical term used to describe a range of mental and physical disabilities caused by maternal alcohol consumption. The role of alcohol as a teratogen and its effects on the cellular growth of the embryo and the fetus were not determined on scientific grounds until the late 1960s. However, the link between alcohol use during…
| Jasmine Brown, Roger Bland, Egon Jonsson, Andrew Greenshaw
Objective: Fetal Alcohol Spectrum Disorder (FASD) is a preventable disorder caused by maternal alcohol consumption and marked by a range of physical and mental disabilities. Although recognized by the scientific and medical community as a clinical disorder, no internationally standardized diagnostic tool yet exists for FASD. Methods and Results: This review seeks to analyse the…
| Charles Yan, Yufei Zheng, Michael D. Hill, Balraj Mann, Thomas Jeerakathil, Noreen Kamal, Shy Amlani, Anderson Chuck
Abstract: We present a conceptual approach to determine the optimal solution to delivering a health technology, consistent with the objective of maximizing patient outcomes subject to resources available to a publicly funded health system. The article addresses two key policy questions: 1) adding system values through appropriate planning of health services delivery and 2) considering…
As the Federal Government contemplates introducing an element of value-based pricing to the pharmaceutical industry regulatory framework, this report provides an overview of key theoretical and empirical material, to support informed engagement by all stakeholders in this important debate.
22 February 2018 Edmonton, Alberta On February 22nd, 2018 the Institute Health Economics (IHE), the Canadian Agency for Drugs & Technologies in Health (CADTH), and Alberta Health presented a forum: Doing the Right Thing ... Right: Evidence Informing Clinical Decision-Making. The purpose of this event was to provide a platform for shared learning and to showcase CADTH and Alberta…
| Rodger Craig, Carmen Moga, Bing Guo, Dagmara Chojecki
The Institute of Health Economics (IHE) was commissioned by the Canadian Cardiovascular Society to provide a rapid update of the literature, to compare the impacts of public reporting and external benchmarking on selected outcomes, and to evaluate and describe the applicability of this body of research to non- competitive health systems, emphasizing perspectives and considerations…
Objective: The aim of this study was to analyze the health care costs and savings associated with quality improvement (QI) interventions initiated and implemented utilizing the National Surgical Quality Improvement Program (NSQIP). Background: Five acute care facilities of Alberta Health Services (AHS) adopted NSQIP in 2015 for a pilot project. Methods: The cost-savings of NSQIP…
This report provides a summary of the proceedings from the IHE roundtable on diabetes care and management in Indigenous populations in Canada, held on November 1, 2017. The roundtable aimed to: discuss and share learnings and promising practices from successful community-led diabetes programs, highlighting approaches to effectively engage communities to co-develop prevention and…
| Sherilyn Houle, Finlay McAlister, Cynthia Jackevicius, Anderson Chuck, Ross Tsuyuki
BACKGROUND: Pay-for-performance (P4P) is increasingly touted as a means to improve health care quality.
PURPOSE: To evaluate the effect of P4P remuneration targeting individual health careproviders.
6 December 2012 Edmonton, Alberta Value for Money in the Health System was the eighth in the series of Innovation Forums. The keynote speaker, Mr. Don Drummond, Matthews Fellow and Distinguished Visiting Scholar in the School of Policy Studies at Queens University, and a former Associate Deputy Minister of Finance in the Government of Canada, as well as a former Senior Vice President…
Alberta STE Report written under contract with the Alberta Health Technologies Decision Process (AHTDP). This report performs an evaluation of the scientific evidence on the safety, performance, and effectiveness of universal and targeted preschool hearing screening (PHS) to inform the Infant and Preschool Screening Framework being developed by the Community and Public Health (CPH)…
Stroke Prevention and Management in Primary Care: a free forum at the 2012 Accelerating Primary Care Conference Sunday, 18 November 2012 Fairmont Banff Springs Hotel, Banff, Alberta Stroke Update 2012 was a free forum for primary care clinicians, held in conjunction with the annual Accelerating Primary Care conference in Banff, Alberta, November 18, 2012. The forum brought together…
Alberta STE Report written under contract with the Alberta Health Technologies Decision Process (AHTDP). This review focused on the best evidence available on the use of PSVS to detect vision conditions in asymptomatic preschool children (aged from birth to 6 years; not necessarily considered at risk for developing visual impairment) to determine the safety and efficacy/effectiveness…
The EQ-5D is a standardized instrument developed by the EuroQol group for use as a measure of health outcome. It considers five dimensions of health-related quality of life: mobility, self-care, usual activities, pain/discomfort, anxiety/depression. When the need for greater collaboration around implementation and use of the EQ-5D in Alberta was recognized in eary 2012, colleagues…
18 – 19 October 2012 Canmore, Alberta The EQ-5D is a standardized instrument developed by the EuroQol group for use as a measure of health outcome. It considers five dimensions of health-related quality of life: mobility, self-care, usual activities, pain/discomfort, anxiety/depression. When the need for greater collaboration around implementation and use of the EQ-5D in Alberta…
Alberta STE Report written under contract with the Alberta Health Technologies Decision Process (AHTDP). This report is an update of a 2007 report. Permanent congenital hearing impairment/loss (PCHI/PCHL) is one of the most common congenital anomalies found at birth which can lead to delays and deficits in the development of speech, language, cognition, and learning, as well as…
This project is concerned with describing a comprehensive set of HTA products, not the methods used to produce them. The report describes various products produced by HTA agencies and provides a summary of the basic elements of these products, but an in-depth analysis of, or comparison between, the various products in terms of their methodology is beyond its scope. Information…
Background: The aim of this study was to extend an earlier retrospective cohort study of schizophrenia via a prospective study to a follow-up of 34 years, with an emphasis on describing the life-course of the illness.
| Thanh Nguyen, Anderson Chuck, Arto Ohinmaa, Philip Jacobs
Background: The benefits of pharmaceutical innovations are widely diffused; they accrue to the healthcare providers, patients, employers, and manufacturers. We estimate the societal monetary benefits of simvastatin in Canada and its distribution among different beneficiaries overtime.
| Mel Slomp, Philip Jacobs, Arto Ohinmaa, Roger Bland, Ray Block, Carolyn Dewa, Carina Wang
OBJECTIVES: In Canada, most mental health services are embedded in the publichealth care system. Little is known of the cost distribution within the mental healthpopulation. Our study aims to estimate the depression care costs of patients with adepression diagnosis, ranking them by the increasing total depression health carecosts.
| Logan McLeod, JoAnn Kingston-Riechers, Egon Jonsson
Abstract: The potential risks to patient safety in a primary care setting are different than the risks to patient safety in an acute care setting. The main differences arise from the organisational structures of primary care delivery and the greater involvement of patients in their care. To account for these differences, we present the Patient Safety in Primary Care Framework…
Alberta STE Report written under contract with the Alberta Health Technologies Decision Process (AHTDP). This report provides an epidemiological profile of fetal aneuploidy and open neural tube defects (ONTD); describes the patterns of care, utilization trends, and factors affecting the provision of first and second trimester screening (FASTs) services for fetal aneuploidy and…
30 July 2012 Montréal, Québec The concept of “personalized medicine” in health is garnering increased attention. Personalized medicine can be defined as the tailoring of preventive, diagnostic, or therapeutic interventions to the characteristics of an individual or population. This may involve genetic or laboratory biomarker information. As personalized…
This background document outlines the methods used to update the Alberta Clinical Practice Guideline (CPG) for the Evidence-Informed Primary Care Management of Low Back Pain, which was produced as part of the second phase of the Alberta Health Technology Assessment (HTA) Ambassador Program.
Link to Alberta Ambassador Guideline Adaptation Program
For which strategies of suicide prevention is there evidence of effectiveness? This report aims to synthesize research findings from existing systematic reviews to address two questions: What types of preventive interventions have been evaluated in the published literature? Which strategies have good-quality evidence to support them? Limited evidence - as well as variability by…
The concept of “personalized medicine” in health is garnering increased attention. Personalized medicine can be defined as the tailoring of preventive, diagnostic, or therapeutic interventions to the characteristics of an individual or population. This may involve genetic or laboratory biomarker information. As personalized medicine promises to increasingly change the…
Primary Care Management of Headache in Adults1st edition, July 2012Guideline Documents including Full Guideline (Hosted by Towards Optimized Practice (TOP) Alberta)
The guideline was developed as part of the Alberta Ambassador Guideline Adaptation Program (http://www.ihe.ca/research-programs/hta/aagap)
| Sherilyn Houle, Anderson Chuck, Finlay McAlister, Ross Tsuyuki
STUDY OBJECTIVE: To quantify the potential cost savings of a community pharmacy-basedhypertension management program based on the results of the Study of Cardiovascular Risk Intervention by Pharmacists-Hypertension (SCRIP-HTN) study in terms of avoided cardiovascular events-myocardial infarction, stroke, and heart failure hospitalization, and to compare these cost savings…
31 May 2012 Edmonton, Alberta
Social Determinants of Health is the seventh IHE Innovation Forum, a semi-annual event bringing together senior public- and private-sector experts and decision-makers to address health care policy issues.
Key Forum Documents
Innovation Forum VII – Social Determinants of Health – FINAL PROGRAMDownload Final Program
| Bach Tran, Arto Ohinmaa, Anh Duong, Nhan Do, Long Nguyen, Quoc Nguyen, Steve Mills, Philip Jacobs, Stan Houston
PURPOSE: This longitudinal study assessed the changes in drug use patterns and health-related quality of life (HRQL) among HIV-positive drug users in the first methadonemaintenance treatment (MMT) cohort in Vietnam.
| Paula Corabian, Dagmara Chojecki, Christa Harstall
This exploratory report provides a summary of some of the published information on the current status of research in and potential future sphere of activity of nanomedicine (Part I) and an inventory of resources on nanotechnology and nanomedicine (Part II). Over the next 5 to 10 years it is expected that the overall impact of nanomedicine will be multifaceted, with significant…
Alberta STE Report written under contract with the Alberta Health Technologies Decision Process (AHTDP). This report summarizes available key information on the use of bariatric treatments for adult obesity in Alberta and North America (mainly Canada). This analysis was intended to describe the profile of adult obesity (definition, progression, epidemiology, and population dynamics…
Alberta STE Report written under contract with the Alberta Health Technologies Decision Process (AHTDP). This report examines the research evidence on the safety and efficacy of insulin pump therapy, as compared to multiple daily insulin injections, in the treatment of children, adults, and pregnant women diagnosed with type 1 diabetes. The report also analyses the economic impact…
| Carmen Moga, Bing Guo, Don Schopflocher, Christa Harstall
This Methodology Paper summarizes the process, a modified Delphi approach, used to develop a specific checklist for the quality appraisal of case series studies. This work was supplemented with a review of other published checklists and an initial pilot test of the newly developed quality appraisal checklist. Researchers at the Institute of Health Economics with researchers from…
| Anne-Marie Boström, Susan E Slaughter, Dagmara Chojecki, Carole Estabrooks
OBJECTIVES: The recent emphasis on knowledge translation (KT) in health care is based on the premise that quality of care improves when research findings are translated into practice. This study aimed to identify the extent, nature, and settings of KT research pertaining to the care of older adults.
This report describes a framework for evaluating policies developed within the Alberta Health Technologies Decision Process (AHTDP) to strengthen the link between policy development and evidence. The framework was designed as a foundation upon which to build a more detailed and contextualized evaluative process in consultation with all stakeholders who are likely to be affected…
In February 2012, the Canadian Institute for Health Information (CIHI) in partnership with the Institute of Health Economics (IHE) sponsored a two day meeting of content, administrative and research experts to identify the breadth of diagnostic imaging studies that CIHI might feasibly undertake with its data or with data that could be easily obtained. The purpose of this report…
Sponsored by the Institute of Health Economics (IHE) – Methodology Forum Series. Presented at the Health Canada and Canadian Institutes of Health Research Personalised Medicine in Canada: A Multi-Stakeholder Workshop to Examine the Canadian Perspective, January 12, 2012. The specific objectives of this session/workshop were to: Explore issues relevant to economic evaluation…
| Bing Guo, Christa Harstall, Thomas Louie, Sander Veldhuyzen van Zanten, Levinus Dieleman
Aim: To critically appraise the clinical research evidence on the safety and effectiveness of FT compared with standard care in the treatment of patients with CDAD.
6 – 7 February 2012 Edmonton, Alberta As part of the Alberta Ambassador Guideline Adaptation Program, in February 2012, the Canadian Institute for Health Information (CIHI) in partnership with the Institute of Health Economics (IHE) sponsored a two day meeting of content, administrative and research experts to identify the breadth of diagnostic imaging studies that CIHI might feasibly…
From the Introduction: Until four or five decades ago, the clinical consensus about childhood depression was that it did not, and perhaps could not, occur (Lefkowitz & Burton, 1978; Rie, 1966; Rochlin, 1965; Wolfenstein, 1966). In fact, prior to 1960, childhood depression was rarely mentioned in the literature (Cytryn, 2003; Tisher, 2007). A number of studies and conceptualizations…
11 – 12 January 2012 Ottawa, Ontario The IHE has established a series of methodologic forums with the intent of identifying and addressing major methodological challenges in informing policies and decisions around the funding and use of health technologies, in partnership with its private and public stakeholders that are involved in the production of evidence and use of assessment.…
| Carissa Escober-Doran, Philip Jacobs, Carolyn Dewa
This study measures the return on investment for parent training at the pre- or early childhood stage. The purpose is to prevent conduct disorders in childhood, and mental health problems in adolescence and adulthood. The program studied is the Triple P program. The context is a one year birth cohort in Alberta. The costs are for a universal parental training program. The downstream…