The outcome of IHE initiatives is providing better information for developing health policy and best medical practices. IHE disseminates information in many ways. In addition to publications in peer-reviewed journals, IHE produces books and a variety of reports synthesizing information in a particular field.
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| Helena M Earl, Louise Hiller, Anne-Laure Vallier, Shrushma Loi, Karen McAdam, Luke Hughes-Davies, Adrian N Harnett, Mei-Lin Ah-See, Richard Simcock, Daniel Rea, Sanjay Raj, Pamela Woodings, Mark Harries, Donna Howe, Kerry Raynes, Helen B Higgins, Maggie Wilcox, Chris Plummer, Janine Mansi, Ioannis Gounaris, Betania Mahler–Araujo, Elena Provenzano, Anita Chhabra, Jean E Abraham, Carlos Caldas, Peter S Hall, Christopher McCabe, Claire Hulme, David Miles, Andrew M Wardley, David A Cameron
Adjuvant trastuzumab significantly improves outcomes for patients with HER2-positive early breast cancer. The standard treatment duration is 12 months but shorter treatment could provide similar efficacy while reducing toxicities and cost. We aimed to investigate whether 6-month adjuvant trastuzumab treatment is non-inferior to the standard 12-month treatment regarding disease-free…
| Michelle Pollock, Ann Scott, Jennifer Seida, Paula Corabian, Andrew J. Sutton, Mike Paulden, Christopher McCabe, Lisa Tjosvold, Bing Guo
The clinical review and economic evaluation aimed to determine how Oncotype DX and Prosigna can be optimally used to determine which patients with early-stage breast cancer will benefit from adjuvant chemotherapy. This report addresses the following research question: For patients with early-stage (I–III), ER+, HER2?, node-negative or node-positive (one to three nodes) breast…
This environmental scan describes existing initiatives that aim to accelerate the diagnostic phase of cancer care in Alberta, Canada, and internationally. Specifically, it describes their development and implementation, structure and functioning, intended outcomes and effectiveness, costs and cost savings, and enablers and barriers.
| S.P. Bisch, T. Wells, L. Gramlich, P. Faris, X. Wang, Dat Tran, Thanh Nguyen, S. Glaze, P. Chu, P. Ghatage, J. Nation, V. Capstick, H. Steed, J. Sabourin, G. Nelson
The Institute of Health Economics has contributed to a study published in the Journal Gynecologic Oncology. The study described the effects of Enhanced Recovery After Surgery (ERAS) guideline implementation in gynecologic oncology on length of stay, patient outcomes, and economic impact in Alberta. The study compared pre-and post-guideline implementation outcomes at two centers…
| Jasmine Brown, Roger Bland, Egon Jonsson, Andrew Greenshaw
Objective: Fetal alcohol spectrum disorder (FASD) is a medical term used to describe a range of mental and physical disabilities caused by maternal alcohol consumption. The role of alcohol as a teratogen and its effects on the cellular growth of the embryo and the fetus were not determined on scientific grounds until the late 1960s. However, the link between alcohol use during…
| Jasmine Brown, Roger Bland, Egon Jonsson, Andrew Greenshaw
Objective: Fetal Alcohol Spectrum Disorder (FASD) is a preventable disorder caused by maternal alcohol consumption and marked by a range of physical and mental disabilities. Although recognized by the scientific and medical community as a clinical disorder, no internationally standardized diagnostic tool yet exists for FASD. Methods and Results: This review seeks to analyse the…
IHE brochure discussing a study on the use of technology to prevent FASD (fetal alcohol spectrum disorder).
FASD Ongoing Initiative
Prevention of Fetal Alcohol Spectrum Disorder by the Use of Technology Study
Objectives: To estimate the life expectancy and specify the causes of death among people with fetal alcohol syndrome (FAS). Methods: Included were all patients recorded in Alberta provincial databases of inpatients, outpatients, or practitioner claims from 2003 to 2012. People with FAS were identified by ICD-9 code 760.71 and ICD-10 codes Q86.0 and P04.3, and were linked…
We reviewed literature to estimate the costs of Fetal Alcohol Spectrum Disorder (FASD) in the Canadian Criminal Justice System (CJS), and to update the total costs of FASD in Canada. The results suggest FASD is costlier than previous estimates. The costs of FASD associated with the CJS are estimated at $3.9 billion a year, with $1.2 billion for police, $0.4 billion for court,…
This book includes the plenary presentations made at the first international conference on prevention of FASD, which was attended by about 700 people from 35 countries around the globe. The issues addressed are FASD as a priority in health policy making; its prevalence and incidence; strategies for prevention; current applied and basic research in the field; the role of the medical…
Fetal alcohol spectrum disorder (FASD) is of growing concern around the world. A range of disabilities caused by prenatal exposure to alcohol, FASD is estimated to affect 2% to 5% of all newborns in the industrialized countries of Europe and North America, and the rates may be significantly higher in some developing countries and certain defined populations. Epidemiological studies…
| Thanh Nguyen, Egon Jonsson, Jessica Moffatt, Liz Dennett, Anderson Chuck, Shelley Birchard
Abstract: Parent-Child Assistance Program (P-CAP) is a 3-year home visitation/harm reduction intervention to prevent alcohol exposed births, thereby births with fetal alcohol spectrum disorder, among high-risk women. This article used a decision analytic modelling technique to estimate the incremental cost-effectiveness ratio and the net monetary benefit of the P-CAP…
Objectives: To estimate the annual health services utilization (HSU) cost per person with FASD by sex and age; the lifetime HSU cost per person with FASD by sex, and the annual HSU cost of FASD for Alberta by sex.
Alberta STE Report written under contract with the Alberta Health Technologies Decision Process (AHTDP). This report examines the potential role of low dose computed tomography (LDCT) in screening for lung cancer in adults aged 50 years or older in Alberta. Section Authors: Section One – Social and System Demographics Analysis: Bing Guo, Dagmara Chojecki Section Two –…
This informative PowerPoint is publicly available for use as an introductory resource for justice professionals who are seeking an educational tool to assist in group presentations/training regarding involvement of those with Fetal Alcohol Spectrum Disorder (FASD) in the criminal justice system.
Le PowerPoint informative est publiquement disponible pour une utilisation en tant que ressource d'introduction pour les professionnels de la justice qui cherchent un outil pédagogique pour aider à des présentations de groupe / formation concernant la participation de ceux qui ont des troubles causés par l'alcoolisation fœtale (ETCAF ) dans le…
The International Charter on Prevention of FASD has been published in The Lancet Global Health, one of the world’s most influential public-health journals. The Charter – also known as the “Edmonton Charter” – was endorsed at the First International Conference on Prevention of FASD in September 2013.The Edmonton Charter was drafted by senior…
The International Charter on Prevention of FASD has been published in The Lancet Global Health, one of the world’s most influential public-health journals. The Charter – also known as the “Edmonton Charter” – was endorsed at the First International Conference on Prevention of FASD in September 2013.The Edmonton Charter was drafted by senior staff of…
The International Charter on Prevention of FASD has been published in The Lancet Global Health, one of the world’s most influential public-health journals. The Charter – also known as the “Edmonton Charter” – was endorsed at the First International Conference on Prevention of FASD in September 2013.The Edmonton Charter was drafted by senior staff of…
The International Charter on Prevention of FASD has been published in The Lancet Global Health, one of the world’s most influential public-health journals. The Charter – also known as the “Edmonton Charter” – was endorsed at the First International Conference on Prevention of FASD in September 2013.The Edmonton Charter was drafted by senior staff of…
The International Charter on Prevention of FASD has been published in The Lancet Global Health, one of the world’s most influential public-health journals. The Charter – also known as the “Edmonton Charter” – was endorsed at the First International Conference on Prevention of FASD in September 2013.The Edmonton Charter was drafted by senior staff of…
The International Charter on Prevention of FASD has been published in The Lancet Global Health, one of the world’s most influential public-health journals. The Charter – also known as the “Edmonton Charter” – was endorsed at the First International Conference on Prevention of FASD in September 2013.The Edmonton Charter was drafted by senior staff of…
The International Charter on Prevention of FASD has been published in The Lancet Global Health, one of the world’s most influential public-health journals. The Charter – also known as the “Edmonton Charter” – was endorsed at the First International Conference on Prevention of FASD in September 2013.The Edmonton Charter was drafted by senior staff of…
PDF of a PowerPoint presentation by Dr. Malcolm King, SFU Faculty of Health Sciences; CIHR Institute of Aboriginal Peoples’ Health.
First International Conference on the Prevention of FASD
PDF of a PowerPoint presentation by Dr. Joanne Weinberg, Professor and Distinguished University Scholar, University of British Columbia.
First International Conference on the Prevention of FASD
This consensus statement on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD) is the product of a unique IHE Consensus Development Conference held in September 2013. The event was a three-day juried hearing of evidence and scientific findings that allowed for the engagement and collaboration of citizens and decision makers in government and the justice system in addressing…
IHE hosted the First International Conference on Prevention of FASD, September 23 - 25, 2013 in Edmonton, Alberta. More than 800 people were in attendance, including global experts and leaders in the health system, government, and the academic and business communities. Well-known speakers from around the world presented facts and findings from research, and described innovative…
PDF of a PowerPoint presentation by Mr. Jonathan Rudin, Program Director, Aboriginal Legal Services of Toronto; Chair, FASD Justice Committee.
Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD)
PDF of a PowerPoint presentation by The Honourable Judge Sheila Whelan, Provincial Court of Saskatchewan.
Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD)
PDF of a PowerPoint presentation by Ms. Donna Debolt, Social Work Consultant, Edmonton, Alberta.
Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD)
PDF of a PowerPoint presentation by Dr. Gail Andrew, Board Member, Canada FASD Research Network; Medical Site Lead, Pediatrics; Medical Director, FASD Clinical Services; Pediatric Consultant, Glenrose Rehabilitation Hospital.
Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD)
PDF of a PowerPoint presentation by Dr. Stephen Greenspan, Emeritus Professor of Educational Psychology, University of Connecticut; Clinical Professor of Psychiatry, University of Colorado.
Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD)
PDF of a PowerPoint presentation by Dr. Arlin Pachet, Clinical Neuropsychologist, Adjunct Assistant Professor, Department of Psychology, University of Calgary.
Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD)
Alcohol can hurt the brain and body of an unborn baby and cause Fetal Alcohol Spectrum Disorder (FASD), a serious lifelong condition that impacts both the individual and their family. A child with FASD becomes an adult with FASD, facing birth defects, developmental and learning delays and social, educational, and employment challenges.
PDF of a PowerPoint presentation by Dr. Sterling Clarren, CEO and Scientific Director, Canada Northwest FASD Research Network; Clinical Professor of Pediatrics; Faculty of Medicine, University of British Columbia; Clinical Professor of Pediatrics, School of Medicine, University of Washington. Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum…
PDF of a PowerPoint presentation by Dr. Kathy Sulik, Professor of Cell Biology and Physiology; Member of the Bowles Center for Alcohol Studies, University of North Carolina, Chapel Hill, NC, USA.
Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD)
PDF of a PowerPoint presentation by Dr. Philip Jacobs, Professor of Health Economics, Faculty of Medicine, University of Alberta; Director of Research Collaborations, IHE.
Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD)
PDF of a PowerPoint presentation by Ms. Fia Jampolsky, Chair, Yukon Human Rights Commission; Lawyer, Cabott and Cabott, Whitehorse.
Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD)
PDF of a PowerPoint presentation by Dr. Larry Burd, Professor, Department of Pediatrics, University of North Dakota School of Medicine; Director of the North Dakota Fetal Alcohol Syndrome Center and PAS Clinic.
Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD)
PDF of a PowerPoint presentation by Dr. Ab Chudley, Professor, Department of Pediatrics, University of Manitoba; Medical Director, Winnipeg Regional Health Authority Program in Genetics and Metabolism.
Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD)
PDF of a PowerPoint presentation by Dr. Jacqueline Pei, Assistant Professor, Department of Educational Psychology; Assistant Clinical Professor, Department of Pediatrics, University of Alberta.
Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD)
PDF of a PowerPoint presentation by Mr. William Edwards, Deputy Public Defender, Los Angeles County Public Defender's Office.
Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD)
PDF of a PowerPoint presentation by Dr. Allan Manson, Professor, Faculty of Law, Queen's University, Kingston, Ontario.
Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD)
PDF of a PowerPoint presentation by Ms. Patricia MacPherson, Senior Research Manager, Correctional Service of Canada.
Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD)
| Thanh Nguyen, Jessica Moffatt, Philip Jacobs, Anderson Chuck, Egon Jonsson
Objectives: To estimate the break-even effectiveness of the Alberta Fetal Alcohol Spectrum Disorder (FASD) Service Networks in reducing occurrences of secondary disabilities associated with FASD.
| Thanh Nguyen, Egon Jonsson, Jessica Moffatt, Liz Dennett
From the Introduction: In this paper, we report a discussion of available evidence regarding the association between poverty and FASD, and regarding the economic consequences of FASD on individuals and families which may materialize an FASD - poverty trap.
This in-depth book contains an introduction to prevention of FASD and to the different methods that are used. There is also a systematic review of the effectiveness of prevention approaches and an overview of reviews on FASD. The book ends with a chapter called “Five perspectives on prevention of FASD” written by professionals in the field who are working to prevent…
The IHE has produced a book of the proceedings from the Consensus Development Conference: FASD - Across the Lifespan. Hardcover copies are available for purchase at a unit cost of $25.00 CAD plus $2.50 shipping and handling. Click on the Add to Cart button at the bottom of this page to proceed with your purchase. In followup to the conference, the Institute has produced two…
Reflecting the recent increased public awareness of the topic, this is the first and most comprehensive resource for over a decade on the molecular basis, prevalence, treatment options, socioeconomic impact, and prevention strategies of FASD. Edited by world-renowned experts, this compendium includes the latest research results to provide new insights and realistic estimations…
The Consensus Statement on Fetal Alcohol Spectrum Disorder (FASD) - Across the Lifespan was produced by a panel of experts led by the Hon. Anne McLellan, former Deputy Prime Minister of Canada. This consensus statement on fetal alcohol spectrum disorder is the product of a unique conference: The IHE Consensus Development Conference on Fetal Alcohol Spectrum Disorder - Across the…
Le présent énoncé consensuel a été préparé par un panel indépendant de professionnels de la santé et de représentants du milieu universitaire et du public en se fondant sur: les études publiées pertinentes réunies par le Comité scientifique de la conférence pour l’établissement…
PDF of a PowerPoint presentation by Dr. Nancy Poole, Research Associate, British Columbia Centre of Excellence for Women's Health; Research Consultant, Women and Substance Use Issues, British Columbia Women's Hospital.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Ms. Nancy Whitney, Clinical Director, King County Parent-Child Assistance Program, University of Washington.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Dr. Amy Salmon, Managing Director, Canada Northwest FASD Research Network; Clinical Assistant Professor, School of Population and Public Health, Faculty of Medicine, University of British Columbia.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Ms. Audrey McFarlane, Executive Director, Lakeland Centre for Fetal Alcohol Spectrum Disorder.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Prof. Sharon Brintnell, Professor, Department of Occupational Therapy, and Director, Occupational Performance Analysis Unit, Faculty of Rehabilitation Medicine, University of Alberta.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by the Honourable Mary Kate Harvie, Associate Chief Judge, Provincial Court of Manitoba.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Dr. Dorothy Badry, Assistant Professor, Faculty of Social Work, University of Calgary.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Dr. Suzanne Tough, Scientific Director, Alberta Centre for Child, Family and Community Research.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Dr. Philip May, Professor of Sociology and Family and Community Medicine, University of New Mexico; Senior Research Scientist, Center on Alcoholism, Substance Abuse, and Addictions.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Dr. Susan Astley, Professor of Epidemiology/Pediatrics, University of Washington; Director, Washington State Fetal Alcohol Syndrome Diagnostic and Prevention Network.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Dr. Albert Chudley, Medical Director, Winnipeg Regional Health Authority Program in Genetics and Metabolism; Professor, Department of Pediatrics, University of Manitoba.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Dr. Linda Burnside, Executive Director, Disability Programs, Manitoba Family Services and Housing.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Ms. Robin Thurmeier, FASD Resources Researcher, Saskatchewan Prevention Institute.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Dr. June Bergman, Associate Professor, Department of Family Medicine, Faculty of Medicine and Dentistry, University of Calgary.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
Alberta STE Report written under contract with the Alberta Health Technologies Decision Process (AHTDP). This report is about testing for Human Papillomavirus (HPV). HPV is one of the most common sexually transmitted infections and can also cause cervical cancer. Cervical screening aims to reduce cervical cancer incidence and mortality by detecting precancerous lesions early. Until…
Background: Although many programs targeting fetal alcohol spectrum disorder (FASD) are implemented, the province of Alberta is still lacking information on costs of FASD.
Objectives: To estimate the costs of FASD in Alberta based on available US and Canadian research on costs of FASD, and Alberta data.
| David Hailey, Marie-Josée Paquin, Olga Maciejewski, Linda Harris, Ann Casebeer, Gordon Fick, Patti Taschuk, Anthony Fields
Teleoncology: Applications and associated benefits for the adult population. This report determines the current state of evidence on teleoncology applications to improve access to care closer to home for rural patients and families affected by a diagnosis of cancer. It follows an earlier report by Marie-Josée Paquin prepared as part of her participation in the SEARCH Classic…
Institute of Health Economics Working Paper WP 06-02. The purpose of this report is to examine the economic implications for the province if a supplement to the fee schedule were allowed for vacuum-assisted biopsies. NOTE: In 2006 the Alberta Heritage Foundation for Medical Research HTA unit moved to IHE. Documents produced in and prior to 2006 have different formats; the format…
| David Cooke, Meina Dubetz, Rahim Heshmati, Sandra Iftody, Erin McKimmon, Jodi Powers, Robert Lee, Peter Dunscombe
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Initiative #22. We present a model process that will assist health care organizations in developing and implementing a formal management system for learning from incidens. Developed specifically for the Radiation Treatment (RT) Program at the Tom Baker Cancer Centre, a major cancer treatment centre in Calgary, Alberta,…
| Leanne Kmet, Robert Lee, Linda Cook, Diane Lorenzetti, Glenys Godlovitch, Edna Einsiedel
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report. In this systematic review, we have critically reviewed the literature addressing the social, legal and ethical issues related to genetic testing for cancer susceptibility, synthesized current information and identified existing gaps in knowledge. We believe the review will prove valuable to policy- and decision-makers…
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #21. The three objectives of this assessment are to determine the available scientific evidence on: the effective time interval for mammography screening in asymptomatic women aged 50 to 69 years; the effective screening interval in asymptomatic women between the ages of 40 and 49 years; and the mortality rate…
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #18. This report has been prepared following interest by the Alberta Cord Blood Bank in obtaining advice on the comparative effectiveness and costs of different types of stem cell transplantation. Earlier assessments by the Foundation have considered peripheral blood stem cell transplantation and cord blood transplantation.…
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #17. The present report has been prepared as a follow up to the previous assessment because of continued interest in the technology by the health ministry and others. It considers studies that have been reported in the literature since completion of the earlier assessment (1997-1999) and focuses on the efficacy…