The outcome of IHE initiatives is providing better information for developing health policy and best medical practices. IHE disseminates information in many ways. In addition to publications in peer-reviewed journals, IHE produces books and a variety of reports synthesizing information in a particular field.
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Summary: Deliberative processes are a well-established part of health technology assessment (HTA) programs in a number of high- and middle-income countries, and serve to combine complex sets of evidence, perspectives, and values to support open, transparent, and accountable decision making. Nevertheless, there is little documentation and research to inform the development…
| Paula Corabian, Bing Guo, Carmen Moga, Ann Scott
The Health Technology Assessment Program at the Institute of Health Economics has conducted rapid assessments (RAs) since 1993. This information paper draws on this experience and describes the evolution of RA process and products over a 25-year relationship with a single requester to quantify the effects of this partnership on the RAs produced. The aim is to contribute to emergent…
This study originated from discussions on how to translate research findings into conclusions regarding safety and effectiveness in systematic reviews responding to requests from a provincial mechanism for introducing and diffusing publicly funded healthcare technologies. Its objective is to identify prominent and reliable evidence grading systems used in health technology assessment…
This brief outlines some perspectives from the Institute of Health Economics (IHE) based on what we have heard from government, public agencies, and industry, and seeks to summarize the key areas where further clarification and deliberation could be helpful.
On November 1st, 2017, the Institute of Health Economics (IHE) hosted a pan-Canadian roundtable discussion regarding diabetes care and management in indigenous populations in Canada. This event was sponsored through an educational grant from Boehringer Ingelheim Canada, and was developed in consultation with an advisory committee including: Mr. Mehmood Alibhai (Boehringer Ingelheim…
On December 12th, 2016, the Institute of Health Economics (IHE) held a roundtable discussion regarding the role of real-world evidence (RWE) in decision-making in Canada, with a focus on RWE generated for pricing and reimbursement. The meeting brought together 11 representatives of key stakeholders: experts in evidence assessment, payers, and those generating RWE including academia…
This guide has been developed by the information specialists at the Institute of Health Economics in Edmonton Alberta and is intended to facilitate searching for health technology assessments (HTAs) or systematic reviews by providing the list of current and reliable internet-based resources that we regularly use in our work. We have tried as much as possible to match this guide…
In October 2015, we held the first Canadian consensus discussion that led to provisional recommendations regarding special considerations for policy-making and healthcare decisionmaking for interventions in patients with idiopathic pulmonary fibrosis (IPF). The meeting included 11 representatives of key stakeholders: patients, care providers, and policy researchers from across…
The federal Minister of Health, the Honourable Rona Ambrose, announced the creation of the Advisory Panel on Healthcare Innovation (Panel) on June 24, 2014, to examine innovative health care ideas and approaches that exist in Canada and internationally. The Panel’s mandate is to identify promising innovations, here and internationally, which could help Canada reduce growth…
The purpose of this roundtable was to gather a small, select group of thought leaders to engage in informed discourse, which was summarized in a report submitted to the new federal Healthcare Innovation Advisory Panel. This roundtable, created in response to the Federal Healthcare Innovation Advisory Panel’s call for stakeholder input, was an exciting opportunity to…
| Don Husereau, Philip Jacobs, Braden Manns, Ties Hoomans, Deborah Marshall, Robyn Tamblyn
This discussion paper has been produced in response to a request from CIHR Institute of Health Services and Policy Research (CIHR IHSPR). The discussion paper will provide guidance to those tasked with conducting an economic evaluation of complex health system interventions. The guidance will be an elaboration of existing National guidelines for economic evaluation, and serve as…
The Provincial Industry Payer Agreements in an Era of National Purchasing Strategies half-day invitational roundtable was part of the IHE's ongoing Methodology Forum series supported by the Institute of Health Economics, the Alberta government, and industry partners, AstraZeneca, Merck, and Eli Lilly. The event brought together academic experts, industry leaders and senior decision…
The Institute of Health Economics, in partnership with Alberta Enterprise and Advanced Education, Alberta Health, and Eli Lilly Canada, conducted a roundtable to examine the concept of Alberta Health as a Living Laboratory. The ‘Living Laboratory’ concept builds off the recognition of the unique assets and opportunity we have in Alberta, including a single health authority…
This project is concerned with describing a comprehensive set of HTA products, not the methods used to produce them. The report describes various products produced by HTA agencies and provides a summary of the basic elements of these products, but an in-depth analysis of, or comparison between, the various products in terms of their methodology is beyond its scope. Information…
| Carmen Moga, Bing Guo, Don Schopflocher, Christa Harstall
This Methodology Paper summarizes the process, a modified Delphi approach, used to develop a specific checklist for the quality appraisal of case series studies. This work was supplemented with a review of other published checklists and an initial pilot test of the newly developed quality appraisal checklist. Researchers at the Institute of Health Economics with researchers from…
This report describes a framework for evaluating policies developed within the Alberta Health Technologies Decision Process (AHTDP) to strengthen the link between policy development and evidence. The framework was designed as a foundation upon which to build a more detailed and contextualized evaluative process in consultation with all stakeholders who are likely to be affected…
A National Roundtable Discussion on Innovative Approaches to Industry-Payor Agreements took place on April 3th, 2011 at the Fairmont Hotel Vancouver in Vancouver, British Columbia in association with the annual meeting of the Canadian Agency for Drugs and Technologies in Health (CADTH). This one-day invitational event engaged experts, industry leaders and senior decision makers…
The purpose of this paper is to provide background information on "game changing innovations" in support of the February 24, 2011 conference Becoming the Best: Building a Sustainable Health System – Game Changing Health Innovations. It was developed by the Institute of Health Economics and funded by Alberta Health Services (AHS) as part of a future focused analysis of the…
| Deborah Marshall, Paul Rogers, Thomas Rohleder, Sonia Vanderby
This booklet provides an overview of the System Dynamics (SD) approach and its potential applications in improving access to health services and quality of care. The specific application addressed here is the improvement of care of patients with hip and knee osteoarthritis (OA), as this is a pressing issue in Canada today. The specific health system and population addressed here…
The use of the term “comparative effectiveness” (CE) has attracted considerable attention, particularly in the United States. This booklet examines the concept of CE and its relationship to other assessment frameworks.
| Arto Ohinmaa, Carolyn Dewa, Trish Chatterley, Philip Jacobs
The mental health economics literature review shows that about one third of the articles found in the search did not include any or just minimal economic information. The database of 4005 references can be used to analyze the mental health economic literature e.g. by diagnosis, type of economic analysis, treatment, publication year, and targeted population.
The Importance of Measuring Health Related Quality of Life report provides an overview of health-related quality of life (HRQL) measurement to facilitate and understanding of such measures to be used in both clinical practice and research. Health-related quality of life (HRQL) measures have been widely used in health research in recent years and have been the endpoint in many clinical…
| David Hailey, Jeremy Grimshaw, Martin Eccles, Craig Mitton, Carol E. Adair, Emily McKenzie, Scott Patten, Brenda Waye-Perry, Leif Rentzhog, Paul Taenzer, Christa Harstall, Saifee Rashiq, Pamela Barton, Don Schopflocher, Lynda Jobin
Effective Dissemination of Findings from Research contains essays resulting from a workshop on effective dissemination of findings from research organized by the Institute of Health Economics. The publication is intended as one of the many available resources on dissemination of research findings for those interested in the subject. Chapter 3 of this report originally appeared…
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Initiative #24. Health technology assessments (HTAs) routinely identify questions or research ‘gaps’ that are not adequately addressed by the primary research. The unique situation of having an HTA unit housed within a provincial research funding organization provided an ideal setting for linking research…
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Initiative #20. Health Technology Assessment (HTA) is the systematic evaluation of properties, effects and/or other impacts of health care technology. Its primary purpose is to provide objective information to support health care decisions and policy making at the local, regional, national and international levels. NOTE:…
| Margaret Wanke, Don Juzwishin, Richard Thornley, Liza Chan
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Initiative #16. The objectives of this review were: To propose a generic evaluation framework for HTA agencies to strengthen their evaluation capacity. To conduct a review of HTA agencies to understand what aspects of HTA agencies have been evaluated, approaches/methods used, outcomes of hte evaluations and to understand…
| David Cooke, Meina Dubetz, Rahim Heshmati, Sandra Iftody, Erin McKimmon, Jodi Powers, Robert Lee, Peter Dunscombe
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Initiative #22. We present a model process that will assist health care organizations in developing and implementing a formal management system for learning from incidens. Developed specifically for the Radiation Treatment (RT) Program at the Tom Baker Cancer Centre, a major cancer treatment centre in Calgary, Alberta,…
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Initiative #21. Much of the activity and purpose of HTA is related to interaction with organizations and individuals with interests in the technologies that are being considered. The focus is often stakeholders with major financial or operational responsbilities for health technologies, including government authorities,…
Institute of Health Economics Working Paper WP 05-07. The aim of this paper is to compare health in Canada and the United States using a preference-based measure. NOTE: In 2006 the Alberta Heritage Foundation for Medical Research HTA unit moved to IHE. Documents produced in and prior to 2006 have different formats; the format was determined by the agency for which the document…
Institute of Health Economics Working Paper WP 05-03. Missing data is a common problem in studies that collect data on patient-reported outcomes data. This paper reports the methods, results, and an evaluation of one method for imputing missince Centre for Epidemiological Studies-Depression (CES-D) data in a study of health-related quality of life (HRQL) in a cohort of patients…
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Initiative #18. This paper has two specific objectives: to describe some of the challenges of using research evidence to inform healthcare policy making; and to provide policy makers and researchers with a framework or tool that would identify and facilitate the use of research evidence and other information in healthcare…
| Sheri Maddigan, David Feeny, Sumit Majumdar, Karen Farris, Jeffrey Johnson
Institute of Health Economics Working Paper WP 05-02. The purpose of this report was to assess the cross-sectional construct validity of the Health Utilities Mark 3 (HUI3) in type 2 diabetes using population-health survey data. NOTE: In 2006 the Alberta Heritage Foundation for Medical Research HTA unit moved to IHE. Documents produced in and prior to 2006 have different formats;…
| Sheri Maddigan, David Feeny, Sumit Majumdar, Karen Farris, Jeffrey Johnson
Institute of Health Economics Working Paper WP 05-01. The objective of this paper is to assess a broad range of determinants of health to determine which are most strongly associated with health-related quality of life (HRQL) in people with type 2 diabetes. NOTE: In 2006 the Alberta Heritage Foundation for Medical Research HTA unit moved to IHE. Documents produced in and prior…
Alberta Heritage Foundation for Medical Research (AHFMR) Information Paper #23. The activities of the HTA Unit in 2002–2003, as reflected in various types of reports it had produced and related dissemination activities, were reviewed in a paper published in 2004. The paper provided an overview of the effectiveness of the Unit as an aid to its future management, drawing on…
| Robert Lee, Karie-Lynn Kelly, Chris Newcomb, David Cooke, Edidiong Ekaette, Peter Craighead, Peter Dunscombe
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Initiative #15. This paper summarizes the first steps in a research program designed to inform technology assessment and decision-making associated with radiotherapy (treatment of cancer with ionizing radiation) at the Tom Baker Cancer Centre (TBCC) in Calgary, Alberta. NOTE: In 2006 the Alberta Heritage Foundation for…
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Initiative #13. Appraising the quality of evidence is an important, yet difficult task, complicated by the consideration of disparate evidence. Quality checklists for assessing RCTs abound, yet it is acknowledged that even within this single study the reliability, validity, feasibility and utility of the various tools…