The outcome of IHE initiatives is providing better information for developing health policy and best medical practices. IHE disseminates information in many ways. In addition to publications in peer-reviewed journals, IHE produces books and a variety of reports synthesizing information in a particular field.
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| Dat Tran, Ilke Akpinar, Irvin Mayers, Tatiana Makhinova, Philip Jacobs
The objective of this study, published in the International Journal of Chronic Obstructive Pulmonary Disease, was to describe the trends in pharmacologic treatment for patients newly diagnosed with chronic obstructive pulmonary disease (COPD) in Alberta, Canada.
PDF of a PowerPoint presentation by Dr. Carl May, Professor of Medical Sociology at the London School of Hygiene and Tropical Medicine.
Implementation Science Breakfast Plenary
| Charles Yan, Katherine Rittenbach, Sepideh Souri, Peter H. Silverstone
This analysis, published in BMC Psychiatry, aimed to determine cost-effectiveness of a stepped-care pathway for depression in adults in primary care versus standard care (SC), treatment-as-usual (TAU), and online cognitive behavioural therapy (CBT).
| Samuel N. Frempong, Andrew J. Sutton, Clare Davenport, Pelham Barton
The aim of this study, published in PharmacoEconomics – Open, was to conduct an early economic analysis of a hypothetical rapid test for typhoid fever diagnosis in Ghana and identify the necessary characteristics of the test for it to be cost effective in Ghana.
This study, published in PharmacoEconomics – Open, reports exploratory analysis of the provincial and nationwide costs of industry-sponsored drug clinical trials (CTs) in Canada. The costs of industry-sponsored drug CTs completed in 2016 were Can$2.1 billion. In addition to the creation of knowledge, these trials play an important role in alleviating the healthcare cost burden…
| Dat Tran, Thanh Nguyen, Arto Ohinmaa, Irvin Mayers, Philip Jacobs
OBJECTIVES: To examine the resource use and healthcare costs for chronic obstructive pulmonary disease (COPD) in Alberta, Canada between 2008 and 2016 and model the future costs to 2030.
Clinical research is funded by industry, governments, charities, and hospitals. It is important to know the economic commitment of the various funding bodies, but until now there has been no national source available which provides these data. We surveyed the major funders to provide such a measure. There is evidence that government and charity funding of medical research is a…
| Helena M Earl, Louise Hiller, Anne-Laure Vallier, Shrushma Loi, Karen McAdam, Luke Hughes-Davies, Adrian N Harnett, Mei-Lin Ah-See, Richard Simcock, Daniel Rea, Sanjay Raj, Pamela Woodings, Mark Harries, Donna Howe, Kerry Raynes, Helen B Higgins, Maggie Wilcox, Chris Plummer, Janine Mansi, Ioannis Gounaris, Betania Mahler–Araujo, Elena Provenzano, Anita Chhabra, Jean E Abraham, Carlos Caldas, Peter S Hall, Christopher McCabe, Claire Hulme, David Miles, Andrew M Wardley, David A Cameron
Adjuvant trastuzumab significantly improves outcomes for patients with HER2-positive early breast cancer. The standard treatment duration is 12 months but shorter treatment could provide similar efficacy while reducing toxicities and cost. We aimed to investigate whether 6-month adjuvant trastuzumab treatment is non-inferior to the standard 12-month treatment regarding disease-free…
| Michelle Pollock, Ann Scott, Jennifer Seida, Paula Corabian, Andrew J. Sutton, Mike Paulden, Christopher McCabe, Lisa Tjosvold, Bing Guo
The clinical review and economic evaluation aimed to determine how Oncotype DX and Prosigna can be optimally used to determine which patients with early-stage breast cancer will benefit from adjuvant chemotherapy. This report addresses the following research question: For patients with early-stage (I–III), ER+, HER2?, node-negative or node-positive (one to three nodes) breast…
PDF of a PowerPoint presentation by Prof Braunack-Mayer, Head, School of Health and Society, University of Wollongong, Australia.
Big Questions about Big Data Event
| Timothy Caulfield, Alessandro R Marcon, Blake Murdoch, Jasmine Brown, Sarah Tinker Perrault, Jonathan Jarry, Jeremy Snyder, Samantha J Anthony, Stephanie Brooks, Zubin Master, Christen Rachul, Ubaka Ogbogu, Joshua Greenberg, Amy Zarzeczny, Robyn Hyde-Lay
Abstract: Numerous social, economic and academic pressures can have a negative impact on representations of biomedical research. We review several of the forces playing an increasingly pernicious role in how health and science information is interpreted, shared and used, drawing discussions towards the role of narrative. In turn, we explore how aspects of narrative are used in…
| Dat Tran, Thanh Nguyen, Dawn Opgenorth, Xiaoming Wang, Danny Zuege, David A. Zygun, Henry T. Stelfox, Sean M. Bagshaw
This study, published in the Journal of Critical Care, explores the association between strained ICU capacity and healthcare costs, and demonstrates the admissions to ICUs experiencing strain incur incremental costs, attributed to longer hospitalization and physician services.
| Paula Corabian, Bing Guo, Carmen Moga, Ann Scott
This article retrospectively examines the evolution of rapid assessments (RAs) produced by the Health Technology Assessment (HTA) Program at the Institute of Health Economics over its 25-year relationship with a single requester, the Alberta Health Ministry (AHM).
| Paula Corabian, Bing Guo, Carmen Moga, Ann Scott
The Health Technology Assessment Program at the Institute of Health Economics has conducted rapid assessments (RAs) since 1993. This information paper draws on this experience and describes the evolution of RA process and products over a 25-year relationship with a single requester to quantify the effects of this partnership on the RAs produced. The aim is to contribute to emergent…
| Nancy Zuck, John Sproule, Charles Cook, Rebecca Albrecht
Alberta Health initiated the Nurse Practitioner Demonstration Project(s) (NPDP) in 2016 to support access to and further integration of Nurse Practitioners (NPs) into Alberta’s primary health care system. Funding was provided (based on diverse program plans) to the Boyle McCauley Health Centre (BMHC), The Alex Community Health Centre (The Alex), the Calgary Urban Project…
Ce rapport fournit un résumé d’un atelier de sprint sur la conception de données probantes du monde réel (DPMR) qui a eu lieu le 21 octobre 2018 à Toronto, en Ontario. L’atelier a été conçu et offert dans le cadre d’un partenariat entre l’Agence canadienne des médicaments et des technologies…
Since 2000, 5 studies have been published that each purported to estimate aggregate national mental health costs in Canada. Each of these studies used a different method. Our aim was to compare the studies, and we created a framework for the different elements used to assess mental health costs (direct costs, indirect costs, transfer payments, and “human” costs). In…
This report provides a summary of the IHE/CAPT Precision Health workshop that took place on October 22, 2017 in Toronto, Ontario. The intent of the workshop was to identify gaps and opportunities in implementing precision health technologies into the Canadian health system. The workshop was supported by unrestricted grants from Merck Canada and Hoffmann-La Roche Limited.The views…
Presenteeism (reduced productivity at work) is thought to be responsible for large economic costs. Nevertheless, much of the research supporting this is based on self-report questionnaires that have not been adequately evaluated.
| Dat Tran, Ilke Akpinar, Richard Fedorak, Egon Jonsson, John Mackey, Lawrence Richer, Philip Jacobs
Purpose: In pharmaceutical clinical trials, industrial sponsors pay for study drugs and related healthcare services. We conducted a study to determine industry’s economic contribution of these trials to the Alberta healthcare system. Authors and Affiliations: Dat T. Tran1,2; Ilke Akpinar2 ; Richard N. Fedorak3 ; Egon Jonsson2 ; John R. Mackey4 ; Lawrence Richer5 ; Philip…
PDF of a PowerPoint presentation by John Sproule, Senior Policy Director, Institute of Health Economics.
Diabetes Care and Management in Indigenous Populations in Canada: A Pan-Canadian Roundtable
PDF of a PowerPoint presentation by Addie Pryce, Director of Health, Assembly of First Nations.
Diabetes Care and Management in Indigenous Populations in Canada: A Pan-Canadian Roundtable
PDF of a PowerPoint presentation by Hesham Nabih, President, HN Consultants Ltd.
Diabetes Care and Management in Indigenous Populations in Canada: A Pan-Canadian Roundtable
PDF of a PowerPoint presentation by Amelia Tekwatonti McGregor, Elder and Community Advisory Board Member, Kahnawake Schools Diabetes Prevention Project.
Diabetes Care and Management in Indigenous Populations in Canada: A Pan-Canadian Roundtable
PDF of a PowerPoint presentation by Dr. Dean Eurich, Professor, School of Public Health, University of Alberta, and Kari Meneen, Team Lead, RADAR; Diabetes Care Coordinator, OKAKI Health Intelligence Inc.
Diabetes Care and Management in Indigenous Populations in Canada: A Pan-Canadian Roundtable
PDF of a PowerPoint presentation by Ms. Jenney Samuelson, Vermont Blueprint for Health Expansion and Quality Improvement Program (EQuIP).
Health Policy Dialogues
PDF of a PowerPoint presentation by Jennifer Pillay, MSc Student, University of Alberta.
IHE/CAPT Precision Health (PH) Workshop – Integrating Precision Health into the Canadian Health System.
PDF of a PowerPoint presentation by Katherine Bonter, Director of Intellectual Property, Clementia Pharmaceuticals Inc.
IHE/CAPT Precision Health (PH) Workshop – Integrating Precision Health into the Canadian Health System.
PDF of a PowerPoint presentation by Kelly Robinson, Director, Health Products and Food Branch, Health Canada.
IHE/CAPT Precision Health (PH) Workshop – Integrating Precision Health into the Canadian Health System.
| Bing Guo, Paula Corabian, Charles Yan, Lisa Tjosvold
This evidence-based report examines expanding the role of paramedics in the community. It summarizes the various types of community paramedicine programs (characteristics, implementation, and funding sources in other jurisdictions) as well as the safety, effectiveness, and economic outcomes of these paramedic programs towards providing patients with alternate, non-emergency health…
PDF of a PowerPoint presentation by Dr. Des Gorman, Professor of Medicine and Associate Dean, Faculty of Medical and Health Sciences, University of Auckland; Executive Chairman of Health Workforce New Zealand.
Health Policy Dialogues
This lists all the documents/websites relevant to the guideline that are available on the IHE and TOP websites, both clinician and patient resources.
Link to Alberta Ambassador Guideline Adaptation Program
L’IHE dans votre poche 2017 – Guide de statistiques sur l’économie de la santé présente et divise les données les plus récentes en sections portant sur le fardeau économique de la maladie, les ressources en soins de santé, les comportements liés à la santé, l'état de santé, les…
This paper reviews implementation of enhanced recovery after surgery (ERAS) and its financial implications. Literature on clinical outcomes and financial implications were reviewed. Reports from many different surgery types shows that implementation of ERAS reduces complications and shortens hospital stay. These improvements have major impacts on reducing the cost of care even…
Alberta STE Report written under contract with the Alberta Health Technologies Decision Process (AHTDP). This STE report examines the social and system demographics, technological safety and therapeutic efficacy/effectiveness, cost-effectiveness, and budget impact of endovascular therapy for acute ischemic stroke, contextualized to the Alberta setting. Section Authors: Section…
This lists all the documents/websites relevant to the guideline that are available on the IHE and TOP websites, both clinician and patient resources.
Link to Alberta Ambassador Guideline Adaptation Program
This report provides a summary of the IHE Real-World Evidence Roundtable, which took place on December 12, 2016. The intent of the roundtable was to capture initial thinking regarding preferences and perceptions of the use of real-world evidence for pricing and reimbursement of new medicines in Canada and what more may be needed.
This report provides a summary of the IHE Biosimilars Forum engagement exercise that took place on April 23, 2017 in Ottawa, Ontario. The intent of the forum was to identify: options to categorize and consider biosimilars; a process to engage stakeholders to identify place in therapy and further evidence development that may be required; and an approach to knowledge exchange that…
IHE In Your Pocket 2017 – A Handbook of Health Economic Statistics includes the most currently available data, presented in separate sections on the economic burden of illness, health care resources, health behaviours, health status and demographics, and health system performance. IHE In Your Pocket was designed to provide a compact, comprehensive, and comparative overview…
| Thanh Nguyen, Ilke Akpinar, Jennifer Gratrix, Sabrina Plitt, Petra Smyczek, Ron Read, Philip Jacobs, Tom Wong, Ameeta E Singh
Adding universal rectal screening to urogenital screening should positively impact rectal Chlamydia trachomatis (CT) incidence in affected populations. A dynamic Markov model was used to evaluate costs and outcomes of three rectal CT screening strategies among women attending sexually transmitted infection clinics in Alberta, Canada: universal urogenital-only screening (UG-only),…
PDF of a PowerPoint presentation by Dr. Muhamad Elrashidi, Kern Center Population Health Scholar, Mayo Clinic.
IHE Innovation Forum XVII – Building a Community-Based Health System: Lessons for a Path Forward
PDF of a PowerPoint presentation by Mr. Nigel Edwards, CEO, Nuffield Trust.
IHE Innovation Forum XVII – Building a Community-Based Health System: Lessons for a Path Forward
Alberta Health Services (AHS) has established a number of Strategic Clinical Networks (SCNs) in the province around specific health care topics (e.g., Cardiovascular Health & Stroke) and within areas where care is delivered (e.g., Surgery). The SCNs are the engines of innovation in the health system and have a mandate to find new and innovative ways of delivering care to provide…
PDF of a PowerPoint presentation by Ms. Kim Wieringa, Assistant Deputy Minister, Health Information Systems, Alberta Health.
e-Health Policy Symposium – Towards “Person-Centred” Integrated Health in Alberta
PDF of a PowerPoint presentation by Dr. Doreen Rabi, Clinical Endocrinologist, Associate Professor, University of Calgary.
e-Health Policy Symposium – Towards “Person-Centred” Integrated Health in Alberta
PDF of a PowerPoint presentation by Ms. Kathleen Ness, Assistant Deputy Minister, Health Service Delivery Division, Alberta Health.
e-Health Policy Symposium – Towards “Person-Centred” Integrated Health in Alberta
PDF of a PowerPoint presentation by Dr. Robert Reid, Chief Scientist, Trillium Health Partners, Institute for Better Health, Mississauga, Ontario.
e-Health Policy Symposium – Towards “Person-Centred” Integrated Health in Alberta
PDF of a PowerPoint presentation by Ms. Annamarie Fuchs, IMAGINE Citizens, Collaborating for Health.
e-Health Policy Symposium – Towards “Person-Centred” Integrated Health in Alberta
PDF of a PowerPoint presentation by Dr. Jennifer Zelmer, President, Azimuth Health Group; Editor-in-Chief, Healthcare Policy, Toronto, Ontario.
e-Health Policy Symposium – Towards “Person-Centred” Integrated Health in Alberta
This report provides a summary of recently published information (January 2015 to present) regarding the glucose monitoring technologies that are commercially available in North America, as well as those that are emerging within the next five years (up to 2021).
PDF of a PowerPoint presentation by Dr. Francois Belanger, Vice President, Quality and Chief Medical Officer for Alberta Health Services, and Dr. Blair O'Neill, Associate Chief Medical Officer, Strategic Clinical Networks, Alberta Health Services.
Value in Health Forum: Standards, Quality, and Economics
PDF of a PowerPoint presentation by Dr. Reinhard Busse, Department of Health Care Management, Berlin University of Technology; Co-founder, European Observatory on Health Systems.
Value in Health Forum: Standards, Quality, and Economics
PDF of a PowerPoint presentation by Dr. Murray Ross, Vice President and Lead, Kaiser Health Policy Institute, Kaiser Permanente.
Value in Health Forum: Standards, Quality, and Economics
PDF of a PowerPoint presentation by Dr. Robert Nesse, Senior Medical Advisor, Healthcare Policy and Payment Reform for Mayo Clinic.
Value in Health Forum: Standards, Quality, and Economics
PDF of a PowerPoint presentation by Dr. Meredith Rosenthal, Professor of Economics and Associate Dean, School of Public Health, Harvard University.
Value in Health Forum: Standards, Quality, and Economics
PDF of a PowerPoint presentation by Dr. Richard Glazier, Senior Core Scientest and Chair of the Primary Care and Population Health Program at ICES.
Value in Health Forum: Standards, Quality, and Economics
| Alain Lesage, Roger Bland, Ian Musgrave, Egon Jonsson, Mike Kirby, Helen-Maria Vasiliadis
The Liberal government committed to making mental health services more accessible. Housing funding was increased in the last budget, but now commitment to comprehensive home care for the severely mentally ill and access to primary care treatments for common mental disorders are needed.
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #32. The aim of this report was to critically appraise and synthesise the published evidence regarding the short- and long-term efficacy/effectiveness of surgical techniques for patients with deep venous incompetence, and attendant skin changes/ulceration, that is refractory to standard care. Information Specialist:…
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #31. This report was prepared in response to a request from Alberta Health and Wellness (AHW) for information about the use of islet cell transplantation for patients with type 1 diabetes. AHW was specifically interested in the current status of islet cell transplantation using the Edmonton protocol for a sub-population…
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #28. This report provides an overview of the evidence from systematic reviews on the effectiveness of suicide prevention strategies. NOTE: In 2006 the Alberta Heritage Foundation for Medical Research HTA unit moved to IHE. Documents produced in and prior to 2006 have different formats; the format was determined…
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #30. Using the 1996 National Population Health survey data, this report provides an estimate of the prevalence of chronic pain (CP) among Albertans. It was estimated that 11.2% of Albertans suffer some level of CP and about 2.3% suffer from severe CP. As the proportion of individuals suffering from CP increases…