The outcome of IHE initiatives is providing better information for developing health policy and best medical practices. IHE disseminates information in many ways. In addition to publications in peer-reviewed journals, IHE produces books and a variety of reports synthesizing information in a particular field.
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| Dat Tran, Ilke Akpinar, Irvin Mayers, Tatiana Makhinova, Philip Jacobs
The objective of this study, published in the International Journal of Chronic Obstructive Pulmonary Disease, was to describe the trends in pharmacologic treatment for patients newly diagnosed with chronic obstructive pulmonary disease (COPD) in Alberta, Canada.
PDF of a PowerPoint presentation by Dr. Carl May, Professor of Medical Sociology at the London School of Hygiene and Tropical Medicine.
Implementation Science Breakfast Plenary
| Charles Yan, Katherine Rittenbach, Sepideh Souri, Peter H. Silverstone
This analysis, published in BMC Psychiatry, aimed to determine cost-effectiveness of a stepped-care pathway for depression in adults in primary care versus standard care (SC), treatment-as-usual (TAU), and online cognitive behavioural therapy (CBT).
| Samuel N. Frempong, Andrew J. Sutton, Clare Davenport, Pelham Barton
The aim of this study, published in PharmacoEconomics – Open, was to conduct an early economic analysis of a hypothetical rapid test for typhoid fever diagnosis in Ghana and identify the necessary characteristics of the test for it to be cost effective in Ghana.
This study, published in PharmacoEconomics – Open, reports exploratory analysis of the provincial and nationwide costs of industry-sponsored drug clinical trials (CTs) in Canada. The costs of industry-sponsored drug CTs completed in 2016 were Can$2.1 billion. In addition to the creation of knowledge, these trials play an important role in alleviating the healthcare cost burden…
| Dat Tran, Thanh Nguyen, Arto Ohinmaa, Irvin Mayers, Philip Jacobs
OBJECTIVES: To examine the resource use and healthcare costs for chronic obstructive pulmonary disease (COPD) in Alberta, Canada between 2008 and 2016 and model the future costs to 2030.
Clinical research is funded by industry, governments, charities, and hospitals. It is important to know the economic commitment of the various funding bodies, but until now there has been no national source available which provides these data. We surveyed the major funders to provide such a measure. There is evidence that government and charity funding of medical research is a…
| Helena M Earl, Louise Hiller, Anne-Laure Vallier, Shrushma Loi, Karen McAdam, Luke Hughes-Davies, Adrian N Harnett, Mei-Lin Ah-See, Richard Simcock, Daniel Rea, Sanjay Raj, Pamela Woodings, Mark Harries, Donna Howe, Kerry Raynes, Helen B Higgins, Maggie Wilcox, Chris Plummer, Janine Mansi, Ioannis Gounaris, Betania Mahler–Araujo, Elena Provenzano, Anita Chhabra, Jean E Abraham, Carlos Caldas, Peter S Hall, Christopher McCabe, Claire Hulme, David Miles, Andrew M Wardley, David A Cameron
Adjuvant trastuzumab significantly improves outcomes for patients with HER2-positive early breast cancer. The standard treatment duration is 12 months but shorter treatment could provide similar efficacy while reducing toxicities and cost. We aimed to investigate whether 6-month adjuvant trastuzumab treatment is non-inferior to the standard 12-month treatment regarding disease-free…
| Michelle Pollock, Ann Scott, Jennifer Seida, Paula Corabian, Andrew J. Sutton, Mike Paulden, Christopher McCabe, Lisa Tjosvold, Bing Guo
The clinical review and economic evaluation aimed to determine how Oncotype DX and Prosigna can be optimally used to determine which patients with early-stage breast cancer will benefit from adjuvant chemotherapy. This report addresses the following research question: For patients with early-stage (I–III), ER+, HER2?, node-negative or node-positive (one to three nodes) breast…
PDF of a PowerPoint presentation by Prof Braunack-Mayer, Head, School of Health and Society, University of Wollongong, Australia.
Big Questions about Big Data Event
| Timothy Caulfield, Alessandro R Marcon, Blake Murdoch, Jasmine Brown, Sarah Tinker Perrault, Jonathan Jarry, Jeremy Snyder, Samantha J Anthony, Stephanie Brooks, Zubin Master, Christen Rachul, Ubaka Ogbogu, Joshua Greenberg, Amy Zarzeczny, Robyn Hyde-Lay
Abstract: Numerous social, economic and academic pressures can have a negative impact on representations of biomedical research. We review several of the forces playing an increasingly pernicious role in how health and science information is interpreted, shared and used, drawing discussions towards the role of narrative. In turn, we explore how aspects of narrative are used in…
| Dat Tran, Thanh Nguyen, Dawn Opgenorth, Xiaoming Wang, Danny Zuege, David A. Zygun, Henry T. Stelfox, Sean M. Bagshaw
This study, published in the Journal of Critical Care, explores the association between strained ICU capacity and healthcare costs, and demonstrates the admissions to ICUs experiencing strain incur incremental costs, attributed to longer hospitalization and physician services.
| Paula Corabian, Bing Guo, Carmen Moga, Ann Scott
This article retrospectively examines the evolution of rapid assessments (RAs) produced by the Health Technology Assessment (HTA) Program at the Institute of Health Economics over its 25-year relationship with a single requester, the Alberta Health Ministry (AHM).
| Paula Corabian, Bing Guo, Carmen Moga, Ann Scott
The Health Technology Assessment Program at the Institute of Health Economics has conducted rapid assessments (RAs) since 1993. This information paper draws on this experience and describes the evolution of RA process and products over a 25-year relationship with a single requester to quantify the effects of this partnership on the RAs produced. The aim is to contribute to emergent…
| Nancy Zuck, John Sproule, Charles Cook, Rebecca Albrecht
Alberta Health initiated the Nurse Practitioner Demonstration Project(s) (NPDP) in 2016 to support access to and further integration of Nurse Practitioners (NPs) into Alberta’s primary health care system. Funding was provided (based on diverse program plans) to the Boyle McCauley Health Centre (BMHC), The Alex Community Health Centre (The Alex), the Calgary Urban Project…
Ce rapport fournit un résumé d’un atelier de sprint sur la conception de données probantes du monde réel (DPMR) qui a eu lieu le 21 octobre 2018 à Toronto, en Ontario. L’atelier a été conçu et offert dans le cadre d’un partenariat entre l’Agence canadienne des médicaments et des technologies…
Rationale, aims and objectives: The Appraisal of Guidelines Research and Evaluation (AGREE) instrument is a generic tool for assessing guideline quality. This feasibility study aimed to reduce the ambiguity and subjectivity associated with AGREE item scoring, and to augment the tool's capacity to differentiate between good- and poor-quality guidelines. Note: This is an Alberta…
Emceed by Tom Feasby, the University of Calgary’s Dean of Medicine, this third session considered the following theme: Maximizing Health System Performance: Cost Containment and Improved Efficiency. Speakers from all sectors provided a range of perspectives on Cost Containment and Improved Efficiency.
PDF of a PowerPoint presentation by Dr. Robert Brook, Rand Health.
IHE Innovation Forum III - Maximizing Health System Performance (1): Cost Containment and Improved Efficiency
PDF of a PowerPoint presentation by Mr. Jeff Lozon, CEO Revera Living.
IHE Innovation Forum III - Maximizing Health System Performance (1): Cost Containment and Improved Efficiency
PDF of a PowerPoint presentation by Dr. Stephen Duckett, CEO, Alberta Health Services.
IHE Innovation Forum III - Maximizing Health System Performance (1): Cost Containment and Improved Efficiency
PDF of a PowerPoint presentation by Dr. Dr. Philip Baker, Dean of Medicine, University of Alberta.
IHE Innovation Forum III - Maximizing Health System Performance (1): Cost Containment and Improved Efficiency
The Consensus Statement on Fetal Alcohol Spectrum Disorder (FASD) - Across the Lifespan was produced by a panel of experts led by the Hon. Anne McLellan, former Deputy Prime Minister of Canada. This consensus statement on fetal alcohol spectrum disorder is the product of a unique conference: The IHE Consensus Development Conference on Fetal Alcohol Spectrum Disorder - Across the…
Le présent énoncé consensuel a été préparé par un panel indépendant de professionnels de la santé et de représentants du milieu universitaire et du public en se fondant sur: les études publiées pertinentes réunies par le Comité scientifique de la conférence pour l’établissement…
The Alberta Diabetes Surveillance System (ADSS) was created in 2006 in a partnership between Alberta Health and Wellness (AHW) and the Institute of Health Economics (IHE). The purpose of the ADSS is to provide information about diabetes within the province of Alberta. This information includes the incidence, prevalence and use of health care services for people with diabetes, along…
PDF of a PowerPoint presentation by Dr. Nancy Poole, Research Associate, British Columbia Centre of Excellence for Women's Health; Research Consultant, Women and Substance Use Issues, British Columbia Women's Hospital.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Ms. Nancy Whitney, Clinical Director, King County Parent-Child Assistance Program, University of Washington.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Dr. Amy Salmon, Managing Director, Canada Northwest FASD Research Network; Clinical Assistant Professor, School of Population and Public Health, Faculty of Medicine, University of British Columbia.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Dr. Frank Oberklaid, Director, Centre for Community Child Health, Royal Children's Hospital, and Professor, Pediatrics, University of Melbourne.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Ms. Audrey McFarlane, Executive Director, Lakeland Centre for Fetal Alcohol Spectrum Disorder.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Dr. Elizabeth Bredberg, Education Consultant, Bredberg Research and Consulting in Education.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Dr. Claire Coles, Professor, Department of Psychiatry and Behavioral Sciences and Pediatrics, Emory University School of Medicine; Director, Fetal Alcohol and Drug Exposure Clinic, Marcus Autism Center, Children's Health Care of Atlanta.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Ms. Brenda Bennett, Executive Director, FASD Life's Journey Inc.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Prof. Sharon Brintnell, Professor, Department of Occupational Therapy, and Director, Occupational Performance Analysis Unit, Faculty of Rehabilitation Medicine, University of Alberta.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Dr. John McLennan, Assistant Professor and Child Psychiatry Consultant, Departments of Community Health Sciences, Psychiatry, and Paediatrics, University of Calgary.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by the Honourable Mary Kate Harvie, Associate Chief Judge, Provincial Court of Manitoba.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Dr. Dorothy Badry, Assistant Professor, Faculty of Social Work, University of Calgary.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Dr. Sterling Clarren, CEO and Scientific Director, Canada Northwest FASD Research Network; Clinical Professor of Pediatrics, Faculty of Medicine, University of British Columbia; Clinical Professor of Pediatrics, University of Washington School of Medicine. Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the…
PDF of a PowerPoint presentation by Dr. Sara Jo Nixon, Professor, Department of Psychiatry, University of Florida, Clinical and Translational Science Institute, Biobehavioral Core.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Dr. Gail Andrew, Member, Board of Directors, Canada Northwest FASD Research Network; Medical Site Lead - Pediatrics, Medical Director - FASD Clinical Services and Pediatric Consultant, Pediatric Programs, Glenrose Rehabilitation Hospital.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Dr. Suzanne Tough, Scientific Director, Alberta Centre for Child, Family and Community Research.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Dr. Philip May, Professor of Sociology and Family and Community Medicine, University of New Mexico; Senior Research Scientist, Center on Alcoholism, Substance Abuse, and Addictions.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Dr. Ben Gibbard, Developmental Pediatrician, Alberta Children's Hospital; Assistant Professor, Department of Pediatrics, Faculty of Medicine, University of Calgary.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Dr. Susan Astley, Professor of Epidemiology/Pediatrics, University of Washington; Director, Washington State Fetal Alcohol Syndrome Diagnostic and Prevention Network.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Dr. Albert Chudley, Medical Director, Winnipeg Regional Health Authority Program in Genetics and Metabolism; Professor, Department of Pediatrics, University of Manitoba.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Dr. Joanne Weinberg, Professor and Distinguished University Scholar and Acting Department Head, Cellular and Physiological Sciences, University of British Columbia.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Dr. Phil Jacobs, Professor, Gastroenterology Division, Department of Medicine, University of Alberta; Director of Collaborations, Institute of Health Economics.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Ms. Mary Berube, Director, Intergovernmental Initiatives, Ministry Support Services Division, Alberta Children and Youth Services.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Dr. Linda Burnside, Executive Director, Disability Programs, Manitoba Family Services and Housing.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Mr. Dan Dubovsky, FASD Specialist for the Substance Abuse and Mental Health Services Administration (SAMHSA), FASD Center for Excellence.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Ms. Diane Malbin, Executive Director, Fetal Alcohol Syndrome Consultation, Education and Training Services.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Ms. Robin Thurmeier, FASD Resources Researcher, Saskatchewan Prevention Institute.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
PDF of a PowerPoint presentation by Dr. June Bergman, Associate Professor, Department of Family Medicine, Faculty of Medicine and Dentistry, University of Calgary.
Consensus Development Conference on Fetal Alcohol Spectrum Disorder (FASD): Across the Lifespan
Alcohol can hurt the brain and body of an unborn baby and cause Fetal Alcohol Spectrum Disorder (FASD), a serious lifelong condition that impacts both the individual and their family. A child with FASD becomes an adult with FASD, facing birth defects, developmental and learning delays and social, educational, and employment challenges. The IHE Consensus Development Conference on…
Written by health policy experts, the book gives a comprehensive overview of 8 different national health care systems and focuses in particular on the different approaches to maintain efficiency and to contain overall healthcare costs. Each chapter identifies the 4-5 specific policies with the highest impact for the respective country over the past 20-30 years and the current policy…
PDF of a PowerPoint presentation by Dr. Stephen Duckett, President and CEO, Alberta Health Services.
IHE Innovation Forum II - Making Difficult Decisions
The Institute of Health Economics (IHE) Innovation Forum series reflects one of the key goals of the Institute to promote open debate and dialogue on important issues in the health care system among academia, government, health service executives and industry. The Institute believes that the significant challenges facing the health system will only be addressed if all partners…
PDF of a PowerPoint presentation by Sir Michael Rawlins, Chairman of National Institute of Clinical Excellence, UK.
IHE Innovation Forum II - Making Difficult Decisions
PDF of a PowerPoint presentation by Mr. Gregg Szabo, Executive Director, Policy, Reimbursement & Communicationa, Merck Frosst Canada Ltd.
IHE Innovation Forum II - Making Difficult Decisions
The objective of this report is to assess research evidence on the safety and prognostic value of exercise testing (including electrocardiogram exercise testing and cardiopulmonary exercise testing) for the prediction of cardiac events in patients with chronic diseases including diabetes, chronic obstructive pulmonary disease (COPD), and arthritis. Information Specialist: Trish…
Alberta STE Report written under contract with the Alberta Health Technologies Decision Process (AHTDP). This report is about testing for Human Papillomavirus (HPV). HPV is one of the most common sexually transmitted infections and can also cause cervical cancer. Cervical screening aims to reduce cervical cancer incidence and mortality by detecting precancerous lesions early. Until…
Les estimations indiquent que un canadien sur trois aura un problème de santé mentale durant sa vie. Peu de canadiens réalisent l’impact que la mauvaise santé mentale a sur les familles, les communautés, les systèmes de santé et l’économie. La santé mentale est aussi importante que la santé physique…
| Charles Yan, JoAnn Kingston-Riechers, Anderson Chuck
This report provides information regarding the impact of physician reimbursement models on five dimensions specified in the Provincial Alternate Relationship Plan Program Evaluation. The impact of physician reimbursement models were assessed on the following five dimensions: Health service utilization Access to care Quality of services Patient satisfaction Physician satisfaction…
The use of the term “comparative effectiveness” (CE) has attracted considerable attention, particularly in the United States. This booklet examines the concept of CE and its relationship to other assessment frameworks.
Background: Although many programs targeting fetal alcohol spectrum disorder (FASD) are implemented, the province of Alberta is still lacking information on costs of FASD.
Objectives: To estimate the costs of FASD in Alberta based on available US and Canadian research on costs of FASD, and Alberta data.
| Lisa Bergerman, Paula Corabian, Christa Harstall
The purpose of this report is to advance the area of workplace mental health through a comprehensive synthesis of published research evidence. More specifically, this report examines the evidence on the effectiveness of organizational-level interventions for the prevention of stress in the workplace for adult employees without diagnosed mental illness. The main effectiveness outcomes…
This report on assisted reproductive technologies (ARTs) is a literature review and secondary analyses of administrative health data conducted to provide information on the direct health care costs associated with multiple pregnancies and the potential cost impact of ARTs in Alberta. It examines the impact of multiple pregnancies and Assistive Reproductive Technologies on health…
| Maureen Yunkap Kwankam, David Hailey, Philip Jacobs
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #13. This assessment has been prepared in view of the interest at the University of Alberta Hospital in developing a cord blood banking facility in the province and to provide information to decision makers on the current status of cord blood transplantation (CBT). The principal purpose of the assessment was to…
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #12. This report has been prepared following a request from the provincial Clinical Practice Guidelines Program for information on the accuracy of diagnostic tests for the detection of bacterial vaginosis (BV), vulvovaginal candidiasis (VVC) and trichomoniasis in females of reproductive age. The intention of this…
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #11. This report has been prepared in view of the increasing interest in ultrasound technology for diagnosis of osteoporosis. Until recently, quantitative ultrasound (QUS) was mainly being used in research settings. This procedure is still not covered by provincial fee schedules. The recent FDA pre-marketing approvals…
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #10. This report has been prepared as part of a project to assess the role of high cost functional diagnostic imaging (FDI) and related methods in routine health care. In the present paper, the potential application of four FDI methods to the management of epilepsy is considered. The assessment considered the current…
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #8. This report has been prepared to provide information to health authorities and others on the available evidence on effectiveness of HBOT and the possible economic impact on health care should a second HBO facility be established in the province. Issues addressed in the report include: Whether HBOT has been…
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #9. The present report has been prepared following a request by Alberta Health in relation to referral of patients outside the province for treatment with stereotactic radiosurgery (SRS). There was interest by the department in the comparative effectiveness of the two main approaches to SRS (GK and LINAC) and in…
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #7. This assessment was undertaken at the request of a Regional Health Authority to provide input into a funding decision on a computerized dynamic posturography (CDP) system for use by a rehabilitation department. The focus of this study was restricted to the clinical use of CDP by the rehabilitation community.…