The outcome of IHE initiatives is providing better information for developing health policy and best medical practices. IHE disseminates information in many ways. In addition to publications in peer-reviewed journals, IHE produces books and a variety of reports synthesizing information in a particular field.
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| Dat Tran, Ilke Akpinar, Irvin Mayers, Tatiana Makhinova, Philip Jacobs
The objective of this study, published in the International Journal of Chronic Obstructive Pulmonary Disease, was to describe the trends in pharmacologic treatment for patients newly diagnosed with chronic obstructive pulmonary disease (COPD) in Alberta, Canada.
PDF of a PowerPoint presentation by Dr. Carl May, Professor of Medical Sociology at the London School of Hygiene and Tropical Medicine.
Implementation Science Breakfast Plenary
| Charles Yan, Katherine Rittenbach, Sepideh Souri, Peter H. Silverstone
This analysis, published in BMC Psychiatry, aimed to determine cost-effectiveness of a stepped-care pathway for depression in adults in primary care versus standard care (SC), treatment-as-usual (TAU), and online cognitive behavioural therapy (CBT).
| Samuel N. Frempong, Andrew J. Sutton, Clare Davenport, Pelham Barton
The aim of this study, published in PharmacoEconomics – Open, was to conduct an early economic analysis of a hypothetical rapid test for typhoid fever diagnosis in Ghana and identify the necessary characteristics of the test for it to be cost effective in Ghana.
This study, published in PharmacoEconomics – Open, reports exploratory analysis of the provincial and nationwide costs of industry-sponsored drug clinical trials (CTs) in Canada. The costs of industry-sponsored drug CTs completed in 2016 were Can$2.1 billion. In addition to the creation of knowledge, these trials play an important role in alleviating the healthcare cost burden…
| Dat Tran, Thanh Nguyen, Arto Ohinmaa, Irvin Mayers, Philip Jacobs
OBJECTIVES: To examine the resource use and healthcare costs for chronic obstructive pulmonary disease (COPD) in Alberta, Canada between 2008 and 2016 and model the future costs to 2030.
Clinical research is funded by industry, governments, charities, and hospitals. It is important to know the economic commitment of the various funding bodies, but until now there has been no national source available which provides these data. We surveyed the major funders to provide such a measure. There is evidence that government and charity funding of medical research is a…
| Helena M Earl, Louise Hiller, Anne-Laure Vallier, Shrushma Loi, Karen McAdam, Luke Hughes-Davies, Adrian N Harnett, Mei-Lin Ah-See, Richard Simcock, Daniel Rea, Sanjay Raj, Pamela Woodings, Mark Harries, Donna Howe, Kerry Raynes, Helen B Higgins, Maggie Wilcox, Chris Plummer, Janine Mansi, Ioannis Gounaris, Betania Mahler–Araujo, Elena Provenzano, Anita Chhabra, Jean E Abraham, Carlos Caldas, Peter S Hall, Christopher McCabe, Claire Hulme, David Miles, Andrew M Wardley, David A Cameron
Adjuvant trastuzumab significantly improves outcomes for patients with HER2-positive early breast cancer. The standard treatment duration is 12 months but shorter treatment could provide similar efficacy while reducing toxicities and cost. We aimed to investigate whether 6-month adjuvant trastuzumab treatment is non-inferior to the standard 12-month treatment regarding disease-free…
| Michelle Pollock, Ann Scott, Jennifer Seida, Paula Corabian, Andrew J. Sutton, Mike Paulden, Christopher McCabe, Lisa Tjosvold, Bing Guo
The clinical review and economic evaluation aimed to determine how Oncotype DX and Prosigna can be optimally used to determine which patients with early-stage breast cancer will benefit from adjuvant chemotherapy. This report addresses the following research question: For patients with early-stage (I–III), ER+, HER2?, node-negative or node-positive (one to three nodes) breast…
PDF of a PowerPoint presentation by Prof Braunack-Mayer, Head, School of Health and Society, University of Wollongong, Australia.
Big Questions about Big Data Event
| Timothy Caulfield, Alessandro R Marcon, Blake Murdoch, Jasmine Brown, Sarah Tinker Perrault, Jonathan Jarry, Jeremy Snyder, Samantha J Anthony, Stephanie Brooks, Zubin Master, Christen Rachul, Ubaka Ogbogu, Joshua Greenberg, Amy Zarzeczny, Robyn Hyde-Lay
Abstract: Numerous social, economic and academic pressures can have a negative impact on representations of biomedical research. We review several of the forces playing an increasingly pernicious role in how health and science information is interpreted, shared and used, drawing discussions towards the role of narrative. In turn, we explore how aspects of narrative are used in…
| Dat Tran, Thanh Nguyen, Dawn Opgenorth, Xiaoming Wang, Danny Zuege, David A. Zygun, Henry T. Stelfox, Sean M. Bagshaw
This study, published in the Journal of Critical Care, explores the association between strained ICU capacity and healthcare costs, and demonstrates the admissions to ICUs experiencing strain incur incremental costs, attributed to longer hospitalization and physician services.
| Paula Corabian, Bing Guo, Carmen Moga, Ann Scott
This article retrospectively examines the evolution of rapid assessments (RAs) produced by the Health Technology Assessment (HTA) Program at the Institute of Health Economics over its 25-year relationship with a single requester, the Alberta Health Ministry (AHM).
| John Paul Ekwaru, Arto Ohinmaa, Sarah Loehr, Solmaz Setayeshgar, Thanh Nguyen, Paul J Veugelers
Objective: Public health decision makers not only consider health benefits but also economic implications when articulating and issuing lifestyle recommendations. Whereas various estimates exist for the economic burden of physical inactivity, excess body weight and smoking, estimates of the economic burden associated with our diet are rare. In the present study, we estimated the…
Economic evaluation helps policy makers and healthcare payers make decisions on drug listing, coverage, and reimbursement. When economic evaluations are conducted before a product launch, the prices of the pharmaceuticals have to be forecast.
PDF of a PowerPoint presentation by Dr. Gregory P. Marchildon, Ontario Research Chair in Health Policy and System Design and Professor, Institute of Health, Policy and Evaluation, University of Toronto; Associate Editor of the Health Reform Observer and originating member of the Pan-Canadian Health Reform Analysis Network (PHRAN). IHE Innovation Forum XVI – Controlling Health…
| Thanh Nguyen, Anderson Chuck, Tracy Wasylak, Jeannette Lawrence, Peter Faris, Olle Ljungqvist, Gregg Nelson, Leah Gramlich
BACKGROUND: In February 2013, Alberta Health Services established an Enhanced Recovery After Surgery (ERAS) implementation program for adopting the ERAS Society colorectal guidelines into 6 sites (initial phase) that perform more than 75% of all colorectal surgeries in the province. We conducted an economic evaluation of this initiative to not only determine its cost-effectiveness,…
PDF of a PowerPoint presentation by Mr. Murray Aitken, Senior VP and Executive Director, IMS Institute for Healthcare Informatics.
6 Oct 2016 – IHE Biosimilars Forum
| Arto Ohinmaa, Yufei Zheng, Thomas Jeerakathil, Scott Klarenbach, Unto Häkkinen, Thanh Nguyen, Dan Friesen, Jane Ruseski, Padma Kaul, Ruolz Ariste, Philip Jacobs
OBJECTIVES: This study aimed to evaluate the trends and regional variation of stroke hospital care in 30-day in-hospital mortality, hospital length of stay (LOS), and 1-year total hospitalization cost after implementation of the Alberta Provincial Stroke Strategy.
PDF of a PowerPoint presentation by Mr. Truman Severson, Vice President, Innovation and Business Development, Covenant Health.
IHE Innovation Forum XV – High Needs & High Cost Patients in Healthcare – How do we improve outcomes for these patients?
PDF of a PowerPoint presentation by Dr. Clemens Hong, MD, MPH, Medical Director, Community Health Improvement, Community Health & Integrated Programs, County of Los Angeles Department of Health Services.
IHE Innovation Forum XV – High Needs & High Cost Patients in Healthcare – How do we improve outcomes for these patients?
PDF of a PowerPoint presentation by Dr. Richard Lewanczuk, Senior Medical Director, Provincial Primary Health Care, Alberta Health Services; Professor, Department of Medicine, University of Alberta.
IHE Innovation Forum XV – High Needs & High Cost Patients in Healthcare – How do we improve outcomes for these patients?
| Thanh Nguyen, Justin Ezekowitz, Dat Tran, Padma Kaul
BACKGROUND: Eplerenone has been demonstrated as being cost effective for the treatment of patients with systolic heart failure (HF) and mild symptoms in several jurisdictions; however, its cost effectiveness is unknown in the context of Alberta, Canada.
Objective: The objective of this paper is to estimate the additional mental health service costs incurred within the criminal justice system that are incurred because of people with mental illnesses who go through the system. Our focus is on costs in Alberta.
| Anderson Chuck, Thanh Nguyen, James Wesenberg, Rhada Chari, Robert Wilson, Selikke Janes-Kelley
Objectives: In 2006, the Alberta Ministry of Health issued a policy to implement fetal fibronectin (fFN) testing as a publicly funded service for pregnant women. The goals were to reduce maternity health care utilization and unnecessary treatment, which would result in cost-savings for the health system by more accurately diagnosing false preterm labour. We conducted a post-policy…
PDF of a PowerPoint presentation by Dr. Martin Kolb, MD, PhD, Professor, Division of Respirology, Department of Medicine, McMaster University.
Optimizing Access to Care for Patients with Idiopathic Pulmonary Fibrosis: A Multi-stakeholder National Forum
PDF of a PowerPoint presentation by Dr. Meena Kalluri, MD, Assistant Professor, Division of Pulmonary Medicine, University of Alberta.
Optimizing Access to Care for Patients with Idiopathic Pulmonary Fibrosis: A Multi-stakeholder National Forum
PDF of a PowerPoint presentation by Mr. Robert Davidson, President, Canadian Pulmonary Fibrosis Foundation (CPFF).
Optimizing Access to Care for Patients with Idiopathic Pulmonary Fibrosis: A Multi-stakeholder National Forum
Alberta STE Report written under contract with the Alberta Health Technologies Decision Process (AHTDP). This STE report examines the safety, screening accuracy, therapeutic efficacy/effectiveness, cost-effectiveness, budget impact, and health system readiness of newborn screening for seven conditions (galactosemia, tyrosinemia type I, homocystinuria, sickle cell anemia, sickle…
Objectives: To estimate the life expectancy and specify the causes of death among people with fetal alcohol syndrome (FAS). Methods: Included were all patients recorded in Alberta provincial databases of inpatients, outpatients, or practitioner claims from 2003 to 2012. People with FAS were identified by ICD-9 code 760.71 and ICD-10 codes Q86.0 and P04.3, and were linked…
Abstract: Canada having a universal health insurance plan that provides hospital and physician benefits offers a natural experiment of whether continuity ofcare actually provides lower or higher utilization of services. The question we are evaluating is whether Canadians, who have a regular physician, use more health resources than those who do not have one? Using two statistical…
PDF of a PowerPoint presentation by Dr. William Ghali, MD, MPH, FRCPC, Scientific Director, O'Brien Institute for Public Health.
IHE/O’Brien Physicians as Stewards of Resources: Roles, Responsibilities, and Remuneration Policy Forum
PDF of a PowerPoint presentation by Dr. David Naylor, President Emeritus and Professor of Medicine, University of Toronto.
IHE/O’Brien Physicians as Stewards of Resources: Roles, Responsibilities, and Remuneration Policy Forum
PDF of a PowerPoint presentation by Dr. Peter Kaboli, Hospitalist and Chief of Medicine, Iowa City VA Healthcare System.
IHE/O’Brien Physicians as Stewards of Resources: Roles, Responsibilities, and Remuneration Policy Forum
PDF of a PowerPoint presentation by Dr. David Price, Professor and Chair, Department of Family Medicine, McMaster University.
IHE/O’Brien Physicians as Stewards of Resources: Roles, Responsibilities, and Remuneration Policy Forum
PDF of a PowerPoint presentation by Dr. Sharon Straus, Professor, Department of Medicine, University of Toronto.
IHE/O’Brien Physicians as Stewards of Resources: Roles, Responsibilities, and Remuneration Policy Forum
PDF of a PowerPoint presentation by Dr. Carl Nohr, President, Alberta Medical Association, and Mr. Mike Gormley, Executive Director, Alberta Medical Association.
IHE/O’Brien Physicians as Stewards of Resources: Roles, Responsibilities, and Remuneration Policy Forum
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #36. The objective of this report is to identify the most appropriate investigative protocol, or component of a protocol, for determining the cause(s) of stillbirth and to identify protocols that have been recommended by health authorities and professional associations both within Canada and worldwide. Information…
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #35. The objective of this report is to assess the efficacy and safety of using trigger point injection (TPI) to treat patients with chronic non-malignant musculoskeletal pain, based on a systematic review of the current published evidence, and to determine the current state of the procedure, the feasibility of…
| Sue Ludwig, Patricia Leggett Tait, Christa Harstall
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #22. This review was requested to determine whether conductive education as a learning approach or therapeutic intervention is safe and efficacious for children with disabilities such as cerebral palsy that impact neuromotor functioning. The review also addresses the profile of the child who would benefit from…
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #21. The three objectives of this assessment are to determine the available scientific evidence on: the effective time interval for mammography screening in asymptomatic women aged 50 to 69 years; the effective screening interval in asymptomatic women between the ages of 40 and 49 years; and the mortality rate…
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #18. This report has been prepared following interest by the Alberta Cord Blood Bank in obtaining advice on the comparative effectiveness and costs of different types of stem cell transplantation. Earlier assessments by the Foundation have considered peripheral blood stem cell transplantation and cord blood transplantation.…
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #6. This report provides details of a telepsychiatry pilot project undertaken by the Provincial Mental Health Advisory Board-Central Alberta (PMHAB) in cooperation with four Regional Health Authorities. It supplements an earlier report issued by the Board describing the pilot project evaluation and has been prepared…
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #5. This assessment of computerized gait analysis in the management of children with cerebral palsy (CP) or spina bifida (SB) has been prepared at the request of the Glenrose Hospital, Edmonton. The hospital has already undertaken developmental work towards establishing a gait analysis facility. Advice was sought…
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #4. This outline of issues in the assessment of telehealth is intended as a resource document for health care funders, providers and administrators. Health authorities and others in Alberta face decisions on the procurement and use of this information and communication technology. Such decisions should be informed…
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #3. The intent of this report is to inform medical practitioners and the public on the current status of in vitro fertilization and embryo transfer (IVF-ET) as a treatment for various types of infertility, and on its use and coverage in Canada. The report has been prepared because of the interest and debate regarding…
Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #2. This paper is intended as a short overview of the effectiveness and status of a neurosurgical procedure, posteroventral pallidotomy (PVP), which is used in the treatment of some people with Parkinson's Disease. NOTE: In 2006 the Alberta Heritage Foundation for Medical Research HTA unit moved to IHE. Documents…