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The outcome of IHE initiatives is providing better information for developing health policy and best medical practices. IHE disseminates information in many ways. In addition to publications in peer-reviewed journals, IHE produces books and a variety of reports synthesizing information in a particular field.

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Results for: Methodology Papers

Conducting rapid assessments: Lessons from 25 years of good practice

February 20, 2019

| Paula Corabian, Bing Guo, Carmen Moga, Ann Scott

The Health Technology Assessment Program at the Institute of Health Economics has conducted rapid assessments (RAs) since 1993. This information paper draws on this experience and describes the evolution of RA process and products over a 25-year relationship with a single requester to quantify the effects of this partnership on the RAs produced. The aim is to contribute to emergent…

Evidence grading systems used in health technology assessment practice

August 03, 2018

| Paula Corabian, Lisa Tjosvold, Christa Harstall

This study originated from discussions on how to translate research findings into conclusions regarding safety and effectiveness in systematic reviews responding to requests from a provincial mechanism for introducing and diffusing publicly funded healthcare technologies. Its objective is to identify prominent and reliable evidence grading systems used in health technology assessment…

Health Technology Assessment on the Net: 2016

May 05, 2016

| IHE Institute of Health Economics

This guide has been developed by the information specialists at the Institute of Health Economics in Edmonton Alberta and is intended to facilitate searching for health technology assessments (HTAs) or systematic reviews by providing the list of current and reliable internet-based resources that we regularly use in our work. We have tried as much as possible to match this guide…

Economic Evaluation of Complex Health System Interventions: A Discussion Paper

July 16, 2014

| Don Husereau, Philip Jacobs, Braden Manns, Ties Hoomans, Deborah Marshall, Robyn Tamblyn

This discussion paper has been produced in response to a request from CIHR Institute of Health Services and Policy Research (CIHR IHSPR). The discussion paper will provide guidance to those tasked with conducting an economic evaluation of complex health system interventions. The guidance will be an elaboration of existing National guidelines for economic evaluation, and serve as…

Utilizing Diverse HTA Products in the Alberta Health Technologies Decision Process: Work in Progress

October 04, 2012

| Ann Scott, Christa Harstall

This project is concerned with describing a comprehensive set of HTA products, not the methods used to produce them. The report describes various products produced by HTA agencies and provides a summary of the basic elements of these products, but an in-depth analysis of, or comparison between, the various products in terms of their methodology is beyond its scope. Information…

Development of a quality appraisal tool for case series studies using a modified Delphi technique

March 07, 2012

| Carmen Moga, Bing Guo, Don Schopflocher, Christa Harstall

This Methodology Paper summarizes the process, a modified Delphi approach, used to develop a specific checklist for the quality appraisal of case series studies. This work was supplemented with a review of other published checklists and an initial pilot test of the newly developed quality appraisal checklist. Researchers at the Institute of Health Economics with researchers from…

Frameworks for post-policy implementation review

March 01, 2012

| IHE Institute of Health Economics

This report describes a framework for evaluating policies developed within the Alberta Health Technologies Decision Process (AHTDP) to strengthen the link between policy development and evidence. The framework was designed as a foundation upon which to build a more detailed and contextualized evaluative process in consultation with all stakeholders who are likely to be affected…

System Dynamics Modeling: A Decision Support Tool to Improve Care for Hip & Knee Osteoarthritis

March 26, 2010

| Deborah Marshall, Paul Rogers, Thomas Rohleder, Sonia Vanderby

This booklet provides an overview of the System Dynamics (SD) approach and its potential applications in improving access to health services and quality of care. The specific application addressed here is the improvement of care of patients with hip and knee osteoarthritis (OA), as this is a pressing issue in Canada today. The specific health system and population addressed here…

Comparative Effectiveness: An Overview

February 13, 2009

| David Hailey, Egon Jonsson, Philip Jacobs

The use of the term “comparative effectiveness” (CE) has attracted considerable attention, particularly in the United States. This booklet examines the concept of CE and its relationship to other assessment frameworks.

Review of Mental Health Economics Evaluation Studies

November 01, 2008

| Arto Ohinmaa, Carolyn Dewa, Trish Chatterley, Philip Jacobs

The mental health economics literature review shows that about one third of the articles found in the search did not include any or just minimal economic information. The database of 4005 references can be used to analyze the mental health economic literature e.g. by diagnosis, type of economic analysis, treatment, publication year, and targeted population.

The Importance of Measuring Health Related Quality of Life

September 01, 2008

| Maria Jose Santana, David Feeny

The Importance of Measuring Health Related Quality of Life report provides an overview of health-related quality of life (HRQL) measurement to facilitate and understanding of such measures to be used in both clinical practice and research. Health-related quality of life (HRQL) measures have been widely used in health research in recent years and have been the endpoint in many clinical…

Effective Dissemination of Findings from Research - A Compilation of Essays

June 01, 2008

| David Hailey, Jeremy Grimshaw, Martin Eccles, Craig Mitton, Carol E. Adair, Emily McKenzie, Scott Patten, Brenda Waye-Perry, Leif Rentzhog, Paul Taenzer, Christa Harstall, Saifee Rashiq, Pamela Barton, Don Schopflocher, Lynda Jobin

Effective Dissemination of Findings from Research contains essays resulting from a workshop on effective dissemination of findings from research organized by the Institute of Health Economics. The publication is intended as one of the many available resources on dissemination of research findings for those interested in the subject. Chapter 3 of this report originally appeared…

Using HTA to Identify Research Gaps

September 01, 2006

| Ann Scott, Carmen Moga, Christa Harstall

Alberta Heritage Foundation for Medical Research (AHFMR) HTA Initiative #24. Health technology assessments (HTAs) routinely identify questions or research ‘gaps’ that are not adequately addressed by the primary research. The unique situation of having an HTA unit housed within a provincial research funding organization provided an ideal setting for linking research…

A Guide to Health Technology Assessment in the Palliser Health Region

June 01, 2006

| Laurel Stretch, Edith Amend

Alberta Heritage Foundation for Medical Research (AHFMR) HTA Initiative #20. Health Technology Assessment (HTA) is the systematic evaluation of properties, effects and/or other impacts of health care technology. Its primary purpose is to provide objective information to support health care decisions and policy making at the local, regional, national and international levels. NOTE:…

An Exploratory Review of Evaluations of Health Technology Assessment Agencies

February 01, 2006

| Margaret Wanke, Don Juzwishin, Richard Thornley, Liza Chan

Alberta Heritage Foundation for Medical Research (AHFMR) HTA Initiative #16. The objectives of this review were: To propose a generic evaluation framework for HTA agencies to strengthen their evaluation capacity. To conduct a review of HTA agencies to understand what aspects of HTA agencies have been evaluated, approaches/methods used, outcomes of hte evaluations and to understand…

A Reference Guide for Learning from Incidents in Radiation Treatment

January 01, 2006

| David Cooke, Meina Dubetz, Rahim Heshmati, Sandra Iftody, Erin McKimmon, Jodi Powers, Robert Lee, Peter Dunscombe

Alberta Heritage Foundation for Medical Research (AHFMR) HTA Initiative #22. We present a model process that will assist health care organizations in developing and implementing a formal management system for learning from incidens. Developed specifically for the Radiation Treatment (RT) Program at the Tom Baker Cancer Centre, a major cancer treatment centre in Calgary, Alberta,…

Consumer Involvement in Health Technology Assessment

December 01, 2005

| David Hailey

Alberta Heritage Foundation for Medical Research (AHFMR) HTA Initiative #21. Much of the activity and purpose of HTA is related to interaction with organizations and individuals with interests in the technologies that are being considered. The focus is often stakeholders with major financial or operational responsbilities for health technologies, including government authorities,…

Comparing Health in the US and Canada - Low Income Groups are Less Disadvantaged in the Frozen North

November 01, 2005

| Ken Eng, David Feeny

Institute of Health Economics Working Paper WP 05-07. The aim of this paper is to compare health in Canada and the United States using a preference-based measure. NOTE: In 2006 the Alberta Heritage Foundation for Medical Research HTA unit moved to IHE. Documents produced in and prior to 2006 have different formats; the format was determined by the agency for which the document…

Missing Data and Methods for Imputing Missing Depression Scores - Experience in a Study of Hip Fracture Patients

October 01, 2005

| Ken Eng, Allyson Jones, David Feeny

Institute of Health Economics Working Paper WP 05-03. Missing data is a common problem in studies that collect data on patient-reported outcomes data. This paper reports the methods, results, and an evaluation of one method for imputing missince Centre for Epidemiological Studies-Depression (CES-D) data in a study of health-related quality of life (HRQL) in a cohort of patients…

Bridging the Gap: The Use of Research Evidence in Policy Development

September 01, 2005

| Jon Brehaut, Don Juzwishin

Alberta Heritage Foundation for Medical Research (AHFMR) HTA Initiative #18. This paper has two specific objectives: to describe some of the challenges of using research evidence to inform healthcare policy making; and to provide policy makers and researchers with a framework or tool that would identify and facilitate the use of research evidence and other information in healthcare…

Construct Validity of the Health Utilities Index Mark 3 in Type 2 Diabetes Evidence from a Nationally Representative Sample of Canadians

August 05, 2005

| Sheri Maddigan, David Feeny, Sumit Majumdar, Karen Farris, Jeffrey Johnson

Institute of Health Economics Working Paper WP 05-02. The purpose of this report was to assess the cross-sectional construct validity of the Health Utilities Mark 3 (HUI3) in type 2 diabetes using population-health survey data. NOTE: In 2006 the Alberta Heritage Foundation for Medical Research HTA unit moved to IHE. Documents produced in and prior to 2006 have different formats;…

Understanding Determinants of Health in Type 2 Diabetes

May 01, 2005

| Sheri Maddigan, David Feeny, Sumit Majumdar, Karen Farris, Jeffrey Johnson

Institute of Health Economics Working Paper WP 05-01. The objective of this paper is to assess a broad range of determinants of health to determine which are most strongly associated with health-related quality of life (HRQL) in people with type 2 diabetes. NOTE: In 2006 the Alberta Heritage Foundation for Medical Research HTA unit moved to IHE. Documents produced in and prior…

Review of Health Technology Assessment Products 2003-2004

January 30, 2005

| David Hailey

Alberta Heritage Foundation for Medical Research (AHFMR) Information Paper #23. The activities of the HTA Unit in 2002–2003, as reflected in various types of reports it had produced and related dissemination activities, were reviewed in a paper published in 2004. The paper provided an overview of the effectiveness of the Unit as an aid to its future management, drawing on…

Quantitative Approaches to Patient Safety - Research in Risk Analysis and Risk Management as Applied to Radiotherapy

October 01, 2004

| Robert Lee, Karie-Lynn Kelly, Chris Newcomb, David Cooke, Edidiong Ekaette, Peter Craighead, Peter Dunscombe

Alberta Heritage Foundation for Medical Research (AHFMR) HTA Initiative #15. This paper summarizes the first steps in a research program designed to inform technology assessment and decision-making associated with radiotherapy (treatment of cancer with ionizing radiation) at the Tom Baker Cancer Centre (TBCC) in Calgary, Alberta. NOTE: In 2006 the Alberta Heritage Foundation for…

Standard Quality Assessment Criteria for Evaluating Primary Research Papers from a Variety of Fields

February 01, 2004

| Leanne Kmet, Robert Lee, Linda Cook

Alberta Heritage Foundation for Medical Research (AHFMR) HTA Initiative #13. Appraising the quality of evidence is an important, yet difficult task, complicated by the consideration of disparate evidence. Quality checklists for assessing RCTs abound, yet it is acknowledged that even within this single study the reliability, validity, feasibility and utility of the various tools…

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