2008

Islet Transplantation for the Treatment of Type 1 Diabetes - An update

The purpose of this report is to update an earlier HTA report published in 2003. This report examines the newly published clinical research evidence on the safety and efficacy/effectiveness of islet transplantation in type 1 diabetic patients who have severe hypoglycemia episodes or hyperglycemia unawareness but are without kidney failure. The main clinical efficacy/effectiveness outcomes, insulin independence and/or decrease in hypoglycemia events as a result of the Edmonton protocol, are considered over at least a one-year term or longer.