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    Abstract: The cost of drug development is commonly cited between US$800 and US$1.8 billion. A similar statistic for vaccines is yet to be estimated, and it is unclear whether the cost of vaccines is similar to drug development. Financial and regulatory policy significantly impacts the extent and cost of pharmaceutical development, and as such it is important that…

Objectives: To estimate the monetary benefits of ramipril and its distribution over time among four beneficiaries in Canada: the drug developing manufacturer, generic manufacturers, the healthcare sector and employment sectors.

Speaker Biographies Keynote Speaker Louis Hugo Francescutti, MD, PhD, MPH, FRCPC, FACPM, CCFP, FRCP(Ire), FRCP(Edin), ICD-D, CCPEPresident, Canadian Medical Association, 2013-14 Dr. Louis Francescutti received his combined Doctor of Philosophy (Immunology) in 1985 and Doctor of Medicine in 1987 from the University of Alberta. In 1994, he completed further studies in injury control…

28 November 2013Edmonton, Alberta Welcome and Greetings from the Minister of Health Honourable Fred Horne, Minister of Healthhttp://vimeo.com/channels/907291/81424176  Keynote presentation Let's Talk Health and Not HealthcareDr. Louis Hugo Francescutti, President, Canadian Medical AssociationDownload Presentation http://vimeo.com/channels/907291/81416417  Disclaimer:…

28 November 2013 Edmonton, Alberta Choosing Wisely® in Health Care: A Canadian Perspective is the tenth IHE Innovation Forum, a semi-annual event bringing together senior public- and private-sector decision-makers to address policy issues of importance in the healthcare system in Alberta, Canada, and internationally. Choosing Wisely® is an initiative of the ABIM Foundation…

PDF of a PowerPoint presentation by Dr. Louis Hugo Francescutti, President, Canadian Medical Association. Disclaimer: please be aware that some of these images may be considered very disturbing or graphic to some viewers. IHE Innovation Forum X – Choosing Wisely® in Health Care: A Canadian Perspective

PDF of a PowerPoint presentation by Dr. Sam Shortt, Canadian Medical Association.  IHE Innovation Forum X – Choosing Wisely® in Health Care: A Canadian Perspective

PDF of a PowerPoint presentation by Dr. Richard Lewanczuk, Alberta Health Services.  IHE Innovation Forum X – Choosing Wisely® in Health Care: A Canadian Perspective

PDF of a PowerPoint presentation by Dr. Tom Feasby, University of Calgary.  IHE Innovation Forum X – Choosing Wisely® in Health Care: A Canadian Perspective

PDF of a PowerPoint presentation by Dr. Bill Hnydyk, Alberta Medical Association.  IHE Innovation Forum X – Choosing Wisely® in Health Care: A Canadian Perspective

PDF of a PowerPoint presentation by Ms. Cathy Pryce, Alberta Health Services. IHE Innovation Forum X – Choosing Wisely® in Health Care: A Canadian Perspective

Choosing Wisely® in Health Care: A Canadian Perspective is the tenth IHE Innovation Forum, a semi-annual event bringing together senior public- and private-sector decision-makers to address policy issues of importance in the healthcare system in Alberta, Canada, and internationally. Choosing Wisely® is an initiative of the ABIM Foundation to improve health care in the United…

Headache Diary - Adapted from: Headache Network Canada http://headachenetwork.ca Link to Alberta Ambassador Guideline Adaptation Program

Headache Diary - Adapted from: Headache Network Canada http://headachenetwork.ca Link to Alberta Ambassador Guideline Adaptation Program

  Objectives: To conduct a systematic review of the effectiveness of KT interventions for chronic noncancer pain management.

  Rationale, Aims, and Objectives: The Alberta Ambassador Program (AAP) adapted seven clinical practice guidelines on low back pain (LBP) into a single guideline spanning the continuum of care from prevention and diagnosis through to treatment. The Ambassador adaptation process was evaluated to 1 Identify the major challenges encountered and successful strategies utilized;…

This report is an analysis of the theoretical basis for value-based pricing, relevant international developments, and areas for improvement within Canada’s current patented drug pricing system. This report intends to inform future policy research, advice, and Canadian drug policy discussions regarding the feasibility and implementation of value-based pricing approaches.

  INTRODUCTION: Varicella vaccine was introduced to the infant immunization schedule in each province or territory between 2000 and 2007 as a result of the Canadian ImmunizationStrategy. The impact of vaccinating children against this disease is potentially far reaching, asimmunization may also benefit those segments of the population not immunized. The objective of this paper…

PDF of a PowerPoint presentation by Ms. Anne Guarasci. First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Ms. Melissa Daniels. First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Ms. Holly Johnston. First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Ms. Denise Milne. First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. Thanh Nguyen. First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. Janni Niclasen. First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. William Pelech. First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Ms. Vicki Russell. First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Mr. James Sanders. First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. Christine Werk. First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Ms. Liz Dennett. First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Mr. Deepa Singal, Mrs. Teresa Brown, and Mr. Albert Chudley. First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. Erin Atkinson.  First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Mrs. Mary Berube.  First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. Linda Burnside.  First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Ms. Holly Gammon.  First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. Karen Howell.  First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. Karen Ingersoll.  First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Ms. Jeanette Lequiere-Tough.  First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. Aurelijus Veryga.  First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. Helene Wirzba.  First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Ms. June Oscar.   First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Mrs. Eli Marie Wiig.  First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. Stefania Bazzo. First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. Peter Butt. First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Mr. Jody Allen Crowe. First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. Karen Ingersoll. First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Ms. Danielle Naumann. First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. Trish Reay. First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Ms. Vicki Russell.  First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Ms. Enid Watson. First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. Malcolm King, SFU Faculty of Health Sciences; CIHR Institute of Aboriginal Peoples’ Health.  First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. Akinori Hisashige, Institute of Healthcare Technology Assessment, Japan.  First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. Joanne Weinberg, Professor and Distinguished University Scholar, University of British Columbia.  First International Conference on the Prevention of FASD

23 – 25 September 2013 Edmonton, Alberta IHE hosted the First International Conference on Prevention of FASD, September 23 - 25, 2013 in Edmonton, Alberta. More than 800 people were in attendance, including global experts and leaders in the health system, government, and the academic and business communities. Download the International Charter on the Prevention of FASD Well-known…

Plenary Speakers | Scientific Committee | Steering Subcommittee | Prevention Subcommittee | Organizing Committee Plenary Speakers Keynote Speaker Honorable Alison M. Redford, Q.C., Premier of Alberta, Canada Speakers Susan Astley, PhD, Research Affiliate at the Center on Human Development and Disability, University of Washington Ilona Autti-Rämö,…

Mon 23 Sep 2013 | Tue 24 Sep 2013 | Wed 25 Sep 2013 First International Conference on Prevention of FASD - Final Program Monday, 23 September 2013 8:00 – 12:30 OPENING OF THE CONFERENCE Welcome from the Steering Committee of Alberta Initiatives on FASDEgon Jonsson and Marguerite Trussler http://vimeo.com/channels/907053/77103171 FASD Prevention in a Policy…

Mon 23 Sep 2013 | Tue 24 Sep 2013 | Wed 25 Sep 2013| Other Presentations First International Conference on Prevention of FASD - Final Program Monday, 23 September 2013 13:30 – 15:00 PANEL A PRESENTATIONS  Prevention of FASD in WA State: Evidence of Success (1973-2013) Dr. Susan Astley Download presentation (7.7 MB) Evaluating FASD Prevention…

Download the International Charter on the Prevention of FASD The International Charter on Prevention of FASD has been published in The Lancet Global Health, one of the world’s most influential public-health journals. The Charter – also known as the “Edmonton Charter” – was endorsed at the First International Conference on Prevention of FASD in September…

PDF of a PowerPoint presentation by Dr. Susan Astley.  First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. Deborah Rutman.  First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. Peter Butt.  First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Prof. Sameer Deshpande.  First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. Karen Ingersoll.  First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Ms. Holly Johnston.  First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. Nadia L'Esperance.  First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Ms. Denise Milne.  First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Mrs. Carol Rangel.  First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. Carmen Rasmussen.  First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Ms. Elspeth Ross.  First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. Helene Wirzba.  First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. Trecia Wouldes.  First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. Roger Zoorob.  First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. S. Bazzo. First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Ms. Kelly Coons. First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. Brenda Elias. First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Ms. Jan Hofmann. First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. Fariba Kolahdooz. First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. Kersti Linask. First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. Sheila McDonald. First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Ms. Danielle N. Naumann. First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. William Pelech. First International Conference on the Prevention of FASD

PDF of a PowerPoint presentation by Dr. Fu-Lin Wang.  First International Conference on the Prevention of FASD

This consensus statement on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD) is the product of a unique IHE Consensus Development Conference held in September 2013. The event was a three-day juried hearing of evidence and scientific findings that allowed for the engagement and collaboration of citizens and decision makers in government and the justice system in addressing…

IHE hosted the First International Conference on Prevention of FASD, September 23 - 25, 2013 in Edmonton, Alberta. More than 800 people were in attendance, including global experts and leaders in the health system, government, and the academic and business communities. Well-known speakers from around the world presented facts and findings from research, and described innovative…

PDF of a PowerPoint presentation by Mr. Jonathan Rudin, Program Director, Aboriginal Legal Services of Toronto; Chair, FASD Justice Committee.  Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD)

PDF of a PowerPoint presentation by The Honourable Judge Sheila Whelan, Provincial Court of Saskatchewan.  Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD)

PDF of a PowerPoint presentation by Ms. Donna Debolt, Social Work Consultant, Edmonton, Alberta.  Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD)

PDF of a PowerPoint presentation by Dr. Gail Andrew, Board Member, Canada FASD Research Network; Medical Site Lead, Pediatrics; Medical Director, FASD Clinical Services; Pediatric Consultant, Glenrose Rehabilitation Hospital.  Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD)

PDF of a PowerPoint presentation by Dr. Stephen Greenspan, Emeritus Professor of Educational Psychology, University of Connecticut; Clinical Professor of Psychiatry, University of Colorado.  Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD)

PDF of a PowerPoint presentation by Dr. Arlin Pachet, Clinical Neuropsychologist, Adjunct Assistant Professor, Department of Psychology, University of Calgary.  Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD)

Validation of a quality assessment checklist for case series studies poster presented at the Cochrane Colloquium in Quebec City in September 2013.

18 – 20 September 2013 Edmonton, Alberta Alcohol can hurt the brain and body of an unborn baby and cause Fetal Alcohol Spectrum Disorder (FASD), a serious lifelong condition that impacts both the individual and their family. A child with FASD becomes an adult with FASD, facing birth defects, developmental and learning delays and social, educational, and employment challenges.…

Speakers | Jury | Steering Committee | Legal Subcommittee | Legal Working Group | Youth Ambassadors for FASD Working Group | Organizing Committee  Planning for the Legal Issues Conference was carried out by a Subcommittee co-chaired by Kurt Sandstrom, Assistant Deputy Minister, Legal Services, Alberta Justice and Solicitor General; and Karen…

Program Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD) – Final Program Download Program Consensus Statement Consensus Statement on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD) 2013Download Consensus Statement Media Release 20 September 2013 – FASD Jury calls for changes to legal systemDownload Media Release Conference…

Post Event Interviews What are you taking away from this conference? The Honourable Ian Binnie C.C., Q.C.http://vimeo.com/channels/907053/80933844 Fia Jampolskyhttp://vimeo.com/channels/907053/80932924 Donald Langfordhttp://vimeo.com/channels/907053/80932922 Myles Himmelreichhttp://vimeo.com/channels/907053/80933843 What was the jury experience like at the FASD conference? The…

Wed 18 Sep 2013 | Thu 19 Sep 2013 | Fri 20 Sep 2013 Legal Issues of Fetal Alcohol Spectrum Disorder (FASD) – Final Program Wednesday, 18 September 2013 8:45 – 10:25 QUESTION 1: What are the implications of FASD for the legal system?a) An overview of FASD and its general implications An Introduction to FASDSterling Clarren, CEO and Scientific Director, Canada Northwest…

PDF of a PowerPoint presentation by Ms. Patricia MacPherson, Senior Research Manager, Correctional Service of Canada.  Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD)

Alcohol can hurt the brain and body of an unborn baby and cause Fetal Alcohol Spectrum Disorder (FASD), a serious lifelong condition that impacts both the individual and their family. A child with FASD becomes an adult with FASD, facing birth defects, developmental and learning delays and social, educational, and employment challenges.

PDF of a PowerPoint presentation by Dr. Sterling Clarren, CEO and Scientific Director, Canada Northwest FASD Research Network; Clinical Professor of Pediatrics; Faculty of Medicine, University of British Columbia; Clinical Professor of Pediatrics, School of Medicine, University of Washington.  Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum…

PDF of a PowerPoint presentation by Dr. Kathy Sulik, Professor of Cell Biology and Physiology; Member of the Bowles Center for Alcohol Studies, University of North Carolina, Chapel Hill, NC, USA.  Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD)

PDF of a PowerPoint presentation by Dr. Philip Jacobs, Professor of Health Economics, Faculty of Medicine, University of Alberta; Director of Research Collaborations, IHE.  Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD)

PDF of a PowerPoint presentation by Ms. Fia Jampolsky, Chair, Yukon Human Rights Commission; Lawyer, Cabott and Cabott, Whitehorse.  Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD)

PDF of a PowerPoint presentation by Dr. Larry Burd, Professor, Department of Pediatrics, University of North Dakota School of Medicine; Director of the North Dakota Fetal Alcohol Syndrome Center and PAS Clinic.  Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD)

PDF of a PowerPoint presentation by Dr. Ab Chudley, Professor, Department of Pediatrics, University of Manitoba; Medical Director, Winnipeg Regional Health Authority Program in Genetics and Metabolism.  Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD)

PDF of a PowerPoint presentation by Dr. Jacqueline Pei, Assistant Professor, Department of Educational Psychology; Assistant Clinical Professor, Department of Pediatrics, University of Alberta.  Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD)

PDF of a PowerPoint presentation by Mr. William Edwards, Deputy Public Defender, Los Angeles County Public Defender's Office.  Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD)

PDF of a PowerPoint presentation by Dr. Allan Manson, Professor, Faculty of Law, Queen's University, Kingston, Ontario.  Consensus Development Conference on Legal Issues of Fetal Alcohol Spectrum Disorder (FASD)

This service and evaluation project originated from the Alberta courts via the collaboration of two Alberta Ministries; (1) Alberta Justice & Soliciter General and (2) Alberta Environment and Sustainable Resource Development. The impetus arose when a judge in an environmental protection case observed a need for additional attention to the mental health of workers. An Alberta…

This background document outlines the methods used to develop the Alberta Clinical Practice Guideline (CPG) for Management of Primary Headache in Adults, which was produced as part of the Alberta Ambassador Guideline Adaptation Program. Link to Alberta Ambassador Guideline Adaptation Program

  Objectives: To estimate the break-even effectiveness of the Alberta Fetal Alcohol Spectrum Disorder (FASD) Service Networks in reducing occurrences of secondary disabilities associated with FASD.

Speaker Biographies Keynote Speaker Professor Sir Albert Aynsley-Green Kt.Children's Commissioner for England, 2005-2010 Sir Al Aynsley-Green is one of the world's leading authorities on children's services, child health and childhood. Through his distinguished early career as a pediatric endocrinologist and clinical researcher, he developed a deep interest in the circumstances…

9 May 2013Edmonton, Alberta Introductory Remarks Ms. Robyn Blackadar, President and CEO, Alberta Centre for Child, Family & Community Researchhttp://vimeo.com/channels/907291/66438458  Keynote Presentation Professor Sir Albert Aynsley-Green Kt. Children's Commissioner for England, 2005-2010http://vimeo.com/channels/907291/66486081  Response Dr. April Elliott, Chief…

9 May 2013 Edmonton, Alberta Early Childhood Development: Advancing Children’s Health is the ninth IHE Innovation Forum, a semi-annual event bringing together senior public- and private-sector decision-makers to address policy issues of importance in the healthcare system in Alberta, Canada, and internationally. Key Forum Documents Innovation Forum IX – Early childhood…

Early Childhood Development: Advancing Children’s Health is the ninth IHE Innovation Forum, a semi-annual event bringing together senior public- and private-sector decision-makers to address policy issues of importance in the healthcare system in Alberta, Canada, and internationally.

Early Childhood Development: Advancing Children’s Health is the ninth IHE Innovation Forum, a semi-annual event bringing together senior public- and private-sector decision-makers to address policy issues of importance in the healthcare system in Alberta, Canada, and internationally.

  Abstract: Medical wait time is a top health policy issue in Canada. Reliable data on the referral wait time from primary to specialty care are limited. Existing data on referral wait times are generally self-reported by specialists. In 2008, the Edmonton North Primary Care Network (PCN) developed a Centralized Referral Program, including a specialist database that contains…

5 May 2013 St. John's, Newfoundland The Provincial Industry Payer Agreements in an Era of National Purchasing Strategies Roundtable was a follow-up to a 2011 National Roundtable Discussion on Innovative Approaches to Industry-Payer Agreements held in Vancouver, British Columbia in association with the Canadian Agency for Drugs and Technologies in Health (CADTH) Annual Symposium.…

Biographies Hon. Fred Horne Minister of Health, Government of Alberta Mr. Horne was elected to his second term as a Member of the Legislative Assembly for Edmonton-Rutherford on April 23, 2012. On May 8, 2012, Mr. Horne was appointed as Minister of Health. He had served as Minister of Health and Wellness since October 2011. He also served as a member of the Cabinet Policy Committee…

Sunday, 5 May 2013 St. John's, Newfoundland Opening Remarks Anderson Chuck, Director of Economic Evaluation and Analytics, Institute of Health Economics Greetings from the IHE Board Mark Findlay, AstraZeneca, IHE Board Member Greetings from the Minister Honourable Fred Horne, Minister of Health, Alberta Outline of the Day Chris Henshall, Chair, HTAi Policy Forum Discussions on…

Roundtable Final Report Provincial Industry-Payer Agreements in an Era of National Pricing Strategies – National Roundtable Download Roundtable Final Report  Program Provincial Industry Payer Agreements in an Era of National Purchasing Strategies – Program Download Program Background Document Industry-Payer Agreements for Pharmaceuticals: Backgrounder Download…

The Provincial Industry Payer Agreements in an Era of National Purchasing Strategies half-day invitational roundtable was part of the IHE's ongoing Methodology Forum series supported by the Institute of Health Economics, the Alberta government, and industry partners, AstraZeneca, Merck, and Eli Lilly. The event brought together academic experts, industry leaders and senior decision…

PDF of a PowerPoint presentation by Mr. Eddy Nason, Senior Researcher, Institute of Governance.  Provincial Industry Payer Agreements in an Era of National Purchasing Strategies Roundtable.

PDF of a PowerPoint presentation by Dr. Michael Drummond, Professor of Health Economics, University of York, UK.  Provincial Industry Payer Agreements in an Era of National Purchasing Strategies Roundtable.

PDF of a PowerPoint presentation by Diane McArthur, Assistant Deputy Minister, Ontario Ministry of Health and Long Term Care.  Provincial Industry Payer Agreements in an Era of National Purchasing Strategies Roundtable.

The Provincial Industry Payer Agreements in an Era of National Purchasing Strategies half-day invitational roundtable was part of the IHE's ongoing Methodology Forum series supported by the Institute of Health Economics, the Alberta government, and industry partners, AstraZeneca, Merck, and Eli Lilly. The event brought together academic experts, industry leaders and senior decision…

The Provincial Industry Payer Agreements in an Era of National Purchasing Strategies half-day invitational roundtable was part of the IHE's ongoing Methodology Forum series supported by the Institute of Health Economics, the Alberta government, and industry partners, AstraZeneca, Merck, and Eli Lilly. The event brought together academic experts, industry leaders and senior decision…

This health technology assessment report has been produced in response to a request from Alberta Health (AH) as part of the Alberta Health Technologies Decision Process (AHTDP) to perform an evaluation of the scientific evidence on the safety and effectiveness of TMJ Concepts® and Biomet® Microfixation TMJ prostheses for adults who are indicated for total TMJ replacement.…

Transcutaneous Bilirubinometry for the Screening of Hyperbilirubinemia in Neonates ≥35 Weeks’ Gestation This report was prepared for Alberta Health Services (AHS) and focuses on the published evidence about the safety, test accuracy, and clinical impact of the use of transcutaneous bilirubin (TcB) test for the screening of significant hyperbilirubinemia in term or late…

The review summarizes the current evidence on the safety, efficacy, effectiveness, and potential cost-effectiveness on the use of the BridgePoint Medical System (consisting of the CrossBossTM catheter, StingrayTM catheter, and StingrayTM guidewire) for the recanalization of refractory coronary chronic total occlusions (CTOs). The report also describes the relevant outcomes for…

  From the Introduction: In this paper, we report a discussion of available evidence regarding the association between poverty and FASD, and regarding the economic consequences of FASD on individuals and families which may materialize an FASD - poverty trap.

19 February 2013 Edmonton, Alberta The Institute of Health Economics, in partnership with Alberta Enterprise and Advanced Education, Alberta Health, and Eli Lilly Canada, conducted a roundtable to examine the concept of Alberta Health as a Living Laboratory. The ‘Living Laboratory' concept builds off the recognition of the unique assets and opportunity we have in Alberta,…

Biographies Dr. Lorne Tyrrell Board Chair, Institute of Health Economics Dr. Tyrrell is a former Dean of Medicine and Dentistry at the University of Alberta. He is a co-discoverer of the first oral antiviral drug to treat Hepatitis B. He is the CIHR/GlaxoSmithKline Chair in Virology at the U of A, Chair of the Gairdner Foundation, and a member of the Research Council of the Canadian…

Tuesday, 19 February 2013 Edmonton, Alberta Welcome Dr. Lorne Tyrrell, Chair, Institute of Health Economicshttp://player.vimeo.com/video/60518479 Dr. Michael McGinnis, Executive Director, Roundtable on Value & Science-Driven Health Care, United States Institute of Medicine (IOM)Download Presentation http://player.vimeo.com/video/60607075 Greetings from the Government of…

Background Document Living Laboratory - Backgrounder for Roundtable DiscussionDownload Background Document

The Institute of Health Economics, in partnership with Alberta Enterprise and Advanced Education, Alberta Health, and Eli Lilly Canada, conducted a roundtable to examine the concept of Alberta Health as a Living Laboratory. The ‘Living Laboratory’ concept builds off the recognition of the unique assets and opportunity we have in Alberta, including a single health authority…

PDF of a PowerPoint presentation by Dr. Michael McGinnis, Executive Director, Roundtable on Value & Science-Driven Health Care, United States Institute of Medicine (IOM).  A "Living Laboratory" in Alberta Roundtable.

PDF of a PowerPoint presentation by Dr. Chris Henshall, Board Member, Alberta Research and Innovation Authority.  A "Living Laboratory" in Alberta Roundtable.

PDF of a PowerPoint presentation by Dr. Marvin Fritzler, Chair, Alberta Research and Innovation Authority.  A "Living Laboratory" in Alberta Roundtable.

PDF of a PowerPoint presentation by Dr. Cy Frank, CEO-designate, Alberta Innovates-Health Solutions.  A "Living Laboratory" in Alberta Roundtable.

Alberta STE Report written under contract with the Alberta Health Technologies Decision Process (AHTDP). This report is an update of the 2008 report on islet transplantation (IT) for Type 1 diabetes (T1DM). Section One of this analysis was intended to describe the profile of T1DM (definition, progression, epidemiology, and population dynamics of affected adults in Alberta, in Canada,…

  Purpose: Studies suggest that childhood trauma is linked to both depression and heavy drinking in adulthood, and may create a lifelong vulnerability to stress. Few studies have explored the effects of stress sensitization on the development of depression or heavy drinking among those who have experienced traumatic childhood events. This study aimed to determine the effect…

  BACKGROUND: Pay-for-performance (P4P) is increasingly touted as a means to improve health care quality. PURPOSE: To evaluate the effect of P4P remuneration targeting individual health careproviders.

Speaker Biographies Keynote Speaker Mr. Don DrummondFormer Senior Vice President and Chief Economist, TD Bank Financial Group Don Drummond is the former Senior Vice President and Chief Economist at TD Financial Group. He retired from TD to his current role as Matthews Fellow and Distinguished Visiting Scholar in the School of Policy Studies at Queens University. Prior to joining…

6 December 2012Edmonton, Alberta Introductory Remarks – Government of Alberta Honourable Fred Horne, Minister of Healthhttp://vimeo.com/channels/907291/56013748  Keynote Presentation Mr. Don Drummond, Former Senior Vice President and Chief Economist, TD Bank Financial Grouphttp://vimeo.com/channels/907291/56036522  Panel Discussion ModeratorDr. Annette Trimbee,…

6 December 2012 Edmonton, Alberta Value for Money in the Health System was the eighth in the series of Innovation Forums. The keynote speaker, Mr. Don Drummond, Matthews Fellow and Distinguished Visiting Scholar in the School of Policy Studies at Queens University, and a former Associate Deputy Minister of Finance in the Government of Canada, as well as a former Senior Vice President…

Value for Money in the Health System was the eighth in the series of Innovation Forums. The keynote speaker, Mr. Don Drummond, Matthews Fellow and Distinguished Visiting Scholar in the School of Policy Studies at Queens University, and a former Associate Deputy Minister of Finance in the Government of Canada, as well as a former Senior Vice President and Chief Economics at TD Financial…

Value for Money in the Health System was the eighth in the series of Innovation Forums. The keynote speaker, Mr. Don Drummond, Matthews Fellow and Distinguished Visiting Scholar in the School of Policy Studies at Queens University, and a former Associate Deputy Minister of Finance in the Government of Canada, as well as a former Senior Vice President and Chief Economics at TD Financial…

Alberta STE Report written under contract with the Alberta Health Technologies Decision Process (AHTDP). This report performs an evaluation of the scientific evidence on the safety, performance, and effectiveness of universal and targeted preschool hearing screening (PHS) to inform the Infant and Preschool Screening Framework being developed by the Community and Public Health (CPH)…

Stroke Prevention and Management in Primary Care: a free forum at the 2012 Accelerating Primary Care Conference Sunday, 18 November 2012 Fairmont Banff Springs Hotel, Banff, Alberta Stroke Update 2012 was a free forum for primary care clinicians, held in conjunction with the annual Accelerating Primary Care conference in Banff, Alberta, November 18, 2012. The forum brought together…

Stroke Update 2012 was a free forum for primary care clinicians, held in conjunction with the annual Accelerating Primary Care conference in Banff, Alberta, November 18, 2012. The forum brought together 5 physician leaders to review the current “state of the art” in the rapidly advancing field of stroke prevention and care, with an emphasis on the role of primary care.…

Alberta STE Report written under contract with the Alberta Health Technologies Decision Process (AHTDP). This review focused on the best evidence available on the use of PSVS to detect vision conditions in asymptomatic preschool children (aged from birth to 6 years; not necessarily considered at risk for developing visual impairment) to determine the safety and efficacy/effectiveness…

The EQ-5D is a standardized instrument developed by the EuroQol group for use as a measure of health outcome. It considers five dimensions of health-related quality of life: mobility, self-care, usual activities, pain/discomfort, anxiety/depression. When the need for greater collaboration around implementation and use of the EQ-5D in Alberta was recognized in eary 2012, colleagues…

18 – 19 October 2012 Canmore, Alberta The EQ-5D is a standardized instrument developed by the EuroQol group for use as a measure of health outcome. It considers five dimensions of health-related quality of life: mobility, self-care, usual activities, pain/discomfort, anxiety/depression. When the need for greater collaboration around implementation and use of the EQ-5D in…

Biographies Stirling Bryan National Institute for Health and Clinical Excellence (NICE) Experience with Using the EQ-5D in Economic Analysis Dr. Stirling Bryan is a professor in UBC's School of Population & Public Health, and Director of the Centre for Clinical Epidemiology & Evaluation, Vancouver Coastal Health Research Institute. Dr. Bryan is an economist with a career-long…

Thurs 18 Oct 2012 | Fri 19 Oct 2012 Thursday, 18 October 2012 08:45 – 09:00 Welcome and Opening Remarks Charlene McBrien-Morrison, Executive Director, Health Quality Council of Alberta Steve Buick, Director of Policy and Communications, Institute of Health Economics Kathryn Todd, Senior Vice President, Research, Alberta Health Services 09:00 – 09:30 EQ-5D - Building…

Symposium Proceedings Patient-Reported Outcomes Measurement in Alberta: Potential of the EQ-5D SYMPOSIUM PROCEEDINGS Download Symposium Proceedings 

Alberta STE Report written under contract with the Alberta Health Technologies Decision Process (AHTDP). This report is an update of a 2007 report. Permanent congenital hearing impairment/loss (PCHI/PCHL) is one of the most common congenital anomalies found at birth which can lead to delays and deficits in the development of speech, language, cognition, and learning, as well as…

This project is concerned with describing a comprehensive set of HTA products, not the methods used to produce them. The report describes various products produced by HTA agencies and provides a summary of the basic elements of these products, but an in-depth analysis of, or comparison between, the various products in terms of their methodology is beyond its scope. Information…

  Background: The aim of this study was to extend an earlier retrospective cohort study of schizophrenia via a prospective study to a follow-up of 34 years, with an emphasis on describing the life-course of the illness.

  Background: The benefits of pharmaceutical innovations are widely diffused; they accrue to the healthcare providers, patients, employers, and manufacturers. We estimate the societal monetary benefits of simvastatin in Canada and its distribution among different beneficiaries overtime.

  OBJECTIVES: In Canada, most mental health services are embedded in the publichealth care system. Little is known of the cost distribution within the mental healthpopulation. Our study aims to estimate the depression care costs of patients with adepression diagnosis, ranking them by the increasing total depression health carecosts.

  Abstract: The potential risks to patient safety in a primary care setting are different than the risks to patient safety in an acute care setting. The main differences arise from the organisational structures of primary care delivery and the greater involvement of patients in their care. To account for these differences, we present the Patient Safety in Primary Care Framework…

Alberta STE Report written under contract with the Alberta Health Technologies Decision Process (AHTDP). This report provides an epidemiological profile of fetal aneuploidy and open neural tube defects (ONTD); describes the patterns of care, utilization trends, and factors affecting the provision of first and second trimester screening (FASTs) services for fetal aneuploidy and…

30 July 2012 Montréal, Québec The concept of “personalized medicine” in health is garnering increased attention. Personalized medicine can be defined as the tailoring of preventive, diagnostic, or therapeutic interventions to the characteristics of an individual or population. This may involve genetic or laboratory biomarker information. As personalized…

Monday, 30 July 2012Montréal, Québec Welcome, Introductions, and Overview John Sproule, IHEDon Husereau, University of Ottawa Roundtable Discussion – Assessment of System Readiness Moderator: John Sproule Is the current state of adoption and implementation ideal? What should the goals be for personalized medicine in Canada? What are the components of a vision…

Final Report Personalized Medicine – Policy Gaps and System Readiness: Summary Report of Roundtable Discussion Download Final Report 

This background document outlines the methods used to update the Alberta Clinical Practice Guideline (CPG) for the Evidence-Informed Primary Care Management of Low Back Pain, which was produced as part of the second phase of the Alberta Health Technology Assessment (HTA) Ambassador Program. Link to Alberta Ambassador Guideline Adaptation Program

For which strategies of suicide prevention is there evidence of effectiveness? This report aims to synthesize research findings from existing systematic reviews to address two questions: What types of preventive interventions have been evaluated in the published literature? Which strategies have good-quality evidence to support them? Limited evidence - as well as variability by…

The concept of “personalized medicine” in health is garnering increased attention. Personalized medicine can be defined as the tailoring of preventive, diagnostic, or therapeutic interventions to the characteristics of an individual or population. This may involve genetic or laboratory biomarker information. As personalized medicine promises to increasingly change the…

Primary Care Management of Headache in Adults1st edition, July 2012Guideline Documents including Full Guideline (Hosted by Towards Optimized Practice (TOP) Alberta) The guideline was developed as part of the Alberta Ambassador Guideline Adaptation Program (http://www.ihe.ca/research-programs/hta/aagap)

  STUDY OBJECTIVE: To quantify the potential cost savings of a community pharmacy-basedhypertension management program based on the results of the Study of Cardiovascular Risk Intervention by Pharmacists-Hypertension (SCRIP-HTN) study in terms of avoided cardiovascular events-myocardial infarction, stroke, and heart failure hospitalization, and to compare these cost savings…

31 May 2012 Edmonton, Alberta Social Determinants of Health is the seventh IHE Innovation Forum, a semi-annual event bringing together senior public- and private-sector experts and decision-makers to address health care policy issues. Key Forum Documents Innovation Forum VII – Social Determinants of Health – FINAL PROGRAMDownload Final Program

Speaker Biographies Keynote Speaker Sir Michael MarmotDirector, Institute of Health Equity and MRC Research Professor in Epidemiology, University College London Sir Michael Marmot has led a research group on health inequalities for the past 30 years. He has been invited by the Regional Director of WHO Euro to conduct a European review of health inequalities. At the request of the…

31 May 2012Edmonton, Alberta Welcome and Introductions Dr. Lorne Tyrrell, Chair, Institute of Health EconomicsDownload Presentation http://vimeo.com/channels/907291/44105094  Dr. Chris Mazurkewich, Executive Vice President and CEO, Alberta Health Serviceshttp://vimeo.com/channels/907291/45175125  Honourable David Hancock, Minister of Human Serviceshttp://vimeo.com/channels/907291/44087423 …

PDF of a PowerPoint presentation by Dr. Lorne Tyrrell, Chair, Institute of Health Economics. IHE Innovation Forum VII – Social Determinants of Health

PDF of a PowerPoint presentation by Sir Michael Marmot, Director, Institute of Health Equity and MRC Research Professor in Epidemiology, University College London. IHE Innovation Forum VII – Social Determinants of Health

Social Determinants of Health is the seventh IHE Innovation Forum, a semi-annual event bringing together senior public- and private-sector experts and decision-makers to address health care policy issues.

  PURPOSE: This longitudinal study assessed the changes in drug use patterns and health-related quality of life (HRQL) among HIV-positive drug users in the first methadonemaintenance treatment (MMT) cohort in Vietnam.

This exploratory report provides a summary of some of the published information on the current status of research in and potential future sphere of activity of nanomedicine (Part I) and an inventory of resources on nanotechnology and nanomedicine (Part II). Over the next 5 to 10 years it is expected that the overall impact of nanomedicine will be multifaceted, with significant…

Alberta STE Report written under contract with the Alberta Health Technologies Decision Process (AHTDP). This report summarizes available key information on the use of bariatric treatments for adult obesity in Alberta and North America (mainly Canada). This analysis was intended to describe the profile of adult obesity (definition, progression, epidemiology, and population dynamics…

Alberta STE Report written under contract with the Alberta Health Technologies Decision Process (AHTDP). This report examines the research evidence on the safety and efficacy of insulin pump therapy, as compared to multiple daily insulin injections, in the treatment of children, adults, and pregnant women diagnosed with type 1 diabetes. The report also analyses the economic impact…

This Methodology Paper summarizes the process, a modified Delphi approach, used to develop a specific checklist for the quality appraisal of case series studies. This work was supplemented with a review of other published checklists and an initial pilot test of the newly developed quality appraisal checklist. Researchers at the Institute of Health Economics with researchers from…

  OBJECTIVES: The recent emphasis on knowledge translation (KT) in health care is based on the premise that quality of care improves when research findings are translated into practice. This study aimed to identify the extent, nature, and settings of KT research pertaining to the care of older adults.

This report describes a framework for evaluating policies developed within the Alberta Health Technologies Decision Process (AHTDP) to strengthen the link between policy development and evidence. The framework was designed as a foundation upon which to build a more detailed and contextualized evaluative process in consultation with all stakeholders who are likely to be affected…

In February 2012, the Canadian Institute for Health Information (CIHI) in partnership with the Institute of Health Economics (IHE) sponsored a two day meeting of content, administrative and research experts to identify the breadth of diagnostic imaging studies that CIHI might feasibly undertake with its data or with data that could be easily obtained. The purpose of this report…

Sponsored by the Institute of Health Economics (IHE) – Methodology Forum Series. Presented at the Health Canada and Canadian Institutes of Health Research Personalised Medicine in Canada: A Multi-Stakeholder Workshop to Examine the Canadian Perspective, January 12, 2012. The specific objectives of this session/workshop were to: Explore issues relevant to economic evaluation…

  Aim: To critically appraise the clinical research evidence on the safety and effectiveness of FT compared with standard care in the treatment of patients with CDAD.

Final Summary CIHI/IHE Diagnostic Imaging Invitational Workshop – Meeting SummaryDownload Meeting Summary

6 – 7 February 2012 Edmonton, Alberta As part of the Alberta Ambassador Guideline Adaptation Program, in February 2012, the Canadian Institute for Health Information (CIHI) in partnership with the Institute of Health Economics (IHE) sponsored a two day meeting of content, administrative and research experts to identify the breadth of diagnostic imaging studies that CIHI might…

  From the Introduction: Until four or five decades ago, the clinical consensus about childhood depression was that it did not, and perhaps could not, occur (Lefkowitz & Burton, 1978; Rie, 1966; Rochlin, 1965; Wolfenstein, 1966). In fact, prior to 1960, childhood depression was rarely mentioned in the literature (Cytryn, 2003; Tisher, 2007). A number of studies and conceptualizations…

11 – 12 January 2012 Ottawa, Ontario The IHE has established a series of methodologic forums with the intent of identifying and addressing major methodological challenges in informing policies and decisions around the funding and use of health technologies, in partnership with its private and public stakeholders that are involved in the production of evidence and use of assessment.…

Speakers Dr. Jeffrey Hoch Associate Professor, Department of Health Policy, Management and Evaluation, University of Toronto; Director Pharmacoeconomics Research Unit, Cancer Care Ontario Dr. Stuart Peacock Associate Professor, School of Population and Public Health, University of British Columbia; Co-Director, Canadian Centre for Applied Research in Cancer Control Mr. Don Husereau…

Wednesday – Thursday, 11 – 12 January 2012Ottawa, Ontario Selected Plenary Presentations from Health Canada/CIHR Workshop Measuring Value in Personalized MedicineDr. Deborah Marshallhttp://player.vimeo.com/video/35735037 HTA Assessment in Australia - Challenges for Personalized MedicineDr. Robyn Wardhttp://player.vimeo.com/video/35785570 Stratified Medicine - Observations…

Final Report IHE Methodology Forum: Personalized Medicine – Research Challenge – Health Economics Methodology Forum Summary Download Final Report 

This study measures the return on investment for parent training at the pre- or early childhood stage. The purpose is to prevent conduct disorders in childhood, and mental health problems in adolescence and adulthood. The program studied is the Triple P program. The context is a one year birth cohort in Alberta. The costs are for a universal parental training program. The downstream…