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The outcome of IHE initiatives is providing better information for developing health policy and best medical practices. IHE disseminates information in many ways. In addition to publications in peer-reviewed journals, IHE produces books and a variety of reports synthesizing information in a particular field.

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Results for: Philip Jacobs

Benefit of adjunct universal rectal screening for Chlamydia genital infections in women attending Canadian sexually transmitted infection clinics

May 23, 2017

| Thanh Nguyen, Ilke Akpinar, Jennifer Gratrix, Sabrina Plitt, Petra Smyczek, Ron Read, Philip Jacobs, Tom Wong, Ameeta E Singh

Adding universal rectal screening to urogenital screening should positively impact rectal Chlamydia trachomatis (CT) incidence in affected populations. A dynamic Markov model was used to evaluate costs and outcomes of three rectal CT screening strategies among women attending sexually transmitted infection clinics in Alberta, Canada: universal urogenital-only screening (UG-only),…

Forecasting Pharmaceutical Prices for Economic Evaluations When There Is No Market: A Review

November 08, 2016

| Ilke Akpinar, Philip Jacobs, Tien Dat Tran

Economic evaluation helps policy makers and healthcare payers make decisions on drug listing, coverage, and reimbursement. When economic evaluations are conducted before a product launch, the prices of the pharmaceuticals have to be forecast.

Bringing about change in COPD care – White paper

October 03, 2016

| Arianna Waye, Philip Jacobs

This white paper follows on from the 2016 IHE report, Economic surveillance for chronic obstructive pulmonary disease (COPD) in Alberta. It provides a summary of main gaps in COPD care across Canada and, in the context of a broad economic framework, it surveys important examples of programs and policies designed to address these gaps.

Trends and Regional Variation in Hospital Mortality, Length of Stay and Cost in Hospital of Ischemic Stroke Patients in Alberta Accompanying the Provincial Reorganization of Stroke Care

September 26, 2016

| Arto Ohinmaa, Yufei Zheng, Thomas Jeerakathil, Scott Klarenbach, Unto Häkkinen, Thanh Nguyen, Dan Friesen, Jane Ruseski, Padma Kaul, Ruolz Ariste, Philip Jacobs

  OBJECTIVES: This study aimed to evaluate the trends and regional variation of stroke hospital care in 30-day in-hospital mortality, hospital length of stay (LOS), and 1-year total hospitalization cost after implementation of the Alberta Provincial Stroke Strategy.

Mental health services costs within the Alberta criminal justice system

May 26, 2016

| Alain Lesage, Carolyn Dewa, Jessica Moffatt, Philip Jacobs, Thanh Nguyen, Ting Zhang

  Objective: The objective of this paper is to estimate the additional mental health service costs incurred within the criminal justice system that are incurred because of people with mental illnesses who go through the system. Our focus is on costs in Alberta.

Economic surveillance for chronic obstructive pulmonary disease (COPD) in Alberta

April 12, 2016

| Arianna Waye, Philip Jacobs, Maria Ospina, Michael Stickland, Irvin Mayers

This report provides the results of an economic surveillance analysis on the components of the Alberta healthcare system that are devoted to COPD prevention and treatment. It focuses on epidemiology (prevalence and incidence), service use, and cost indicators, and identifies gaps in the system that presumably add to the overall economic burden of COPD. PDF of the above image:  IHE…

A systematic review of the measurement properties of self-report instruments that assess presenteeism

December 18, 2015

| Angus Thompson, Maria Ospina, Liz Dennett, Arianna Waye, Philip Jacobs

Presenteeism, reduced productivity while working, has come into consideration as a major occupational health problem in many countries with serious consequences for both organizations and employees. Increasing evidence shows that presenteeism represents a significant source of productivity losses that can cost organizations much more than does absenteeism, and it can lead to an…

Palliative care costs in Canada: A descriptive comparison of studies of urban and rural patients near end of life

December 07, 2015

| Serge Dumont, Philip Jacobs, Véronique Turcotte, Stéphane Turcotte, Grace Johnston

  Background: Significant gaps in the evidence base on costs in rural communities in Canada and elsewhere are reported in the literature, particularly regarding costs to families. However, it remains unclear whether the costs related to all resources used by palliative care patients in rural areas differ to those resources used in urban areas.

Medical Device Prices in Economic Evaluations.

May 20, 2015

| Ilke Akpinar, Philip Jacobs, Don Husereau

  Objectives: Economic evaluations, although not formally used in purchasing decisions for medical devices in Canada, are still being conducted and published. The aim of this study was to examine the way that prices have been included in Canadian economic evaluations of medical devices.

A systematic review of measurement properties of instruments assessing presenteeism.

February 01, 2015

| Maria Ospina, Liz Dennett, Arianna Waye, Philip Jacobs, Angus Thompson

  Objectives: To assess and compare the measurement properties (ie, validity, reliability, responsiveness) and the quality of the evidence of presenteeism instruments.

Implementing the Resource in Clinic Program in primary care delivery: a team-based dyad approach.

January 12, 2015

| Lindsay Wodinski, Kate Woodman, Margaret Wanke, Thanh Nguyen, Philip Jacobs

  Abstract: Alberta's Primary Care Networks (PCNs) bring together family physicians and other health professionals to provide local, comprehensive, and readily accessible primary care services to patients. The Edmonton North PCN, one of the largest in the province, piloted the Resource in Clinic (RIC) Program with objectives to increase efficiencies in the use of physician…

Real-life treatment paradigms show infliximab is cost-effective for management of ulcerative colitis

November 12, 2014

| Victoria Ung, Thanh Nguyen, Karen Wong, Karen Kroeker, Thomas Lee, Haili Wang, Arto Ohinmaa, Philip Jacobs, Richard Fedorak

  BACKGROUND & AIMS: Infliximab is effective for induction and maintenance of response in patients with moderate to moderately severe ulcerative colitis. Previous cost analyses of infliximab treatment for ulcerative colitis used models of colectomy vs infliximab and response rates derived from early clinical trials. In real life, therapeutic options are more complex; patients…

How do economic evaluations inform health policy decisions for treatment and prevention in Canada and the United States?

October 15, 2014

| Don Husereau, Anthony Culyer, Peter Neumann, Philip Jacobs

  Abstract: Canadian and US health systems have often been characterized as having vastly different approaches to the financing and delivery of healthcare, with Canada portrayed as more reliant on rationing based on costs. In this article, we examine the similarities and differences between the two countries, the evolution and current role of health economic evaluation, and…

How does burnout affect physician productivity? A systematic literature review

July 28, 2014

| Carolyn Dewa, Desmond Loong, Sarah Bonato, Thanh Nguyen, Philip Jacobs

  BACKGROUND: Interest in the well-being of physicians has increased because of their contributions to the healthcare system quality. There is growing recognition that physicians are exposed to workplace factors that increase the risk of work stress. Long-term exposure to high work stress can result in burnout. Reports from around the world suggest that about one-third to…

Economic Evaluation of Complex Health System Interventions: A Discussion Paper

July 16, 2014

| Don Husereau, Philip Jacobs, Braden Manns, Ties Hoomans, Deborah Marshall, Robyn Tamblyn

This discussion paper has been produced in response to a request from CIHR Institute of Health Services and Policy Research (CIHR IHSPR). The discussion paper will provide guidance to those tasked with conducting an economic evaluation of complex health system interventions. The guidance will be an elaboration of existing National guidelines for economic evaluation, and serve as…

An estimate of the cost of burnout on early retirement and reduction in clinical hours of practicing physicians in Canada

June 13, 2014

| Carolyn Dewa, Philip Jacobs, Thanh Nguyen, Desmond Loong

  BACKGROUND: Interest in the impact of burnout on physicians has been growing because of the possible burden this may have on health care systems. The objective of this study is toestimate the cost of burnout on early retirement and reduction in clinical hours of practicingphysicians in Canada.

Criminal Justice and Forensic Psychiatry Costs in Alberta 2014

June 09, 2014

| Philip Jacobs, Jessica Moffatt, Carolyn Dewa, Thanh Nguyen, Ting Zhang, Alain Lesage

The objective of this paper is to estimate the additional costs to the criminal justice system associated with people with mental illness who go through the system. The focus of the report is on costs in Alberta.

Vaccine development costs: a review

December 02, 2013

| Arianna Waye, Philip Jacobs, Anthony Schryvers

    Abstract: The cost of drug development is commonly cited between US$800 and US$1.8 billion. A similar statistic for vaccines is yet to be estimated, and it is unclear whether the cost of vaccines is similar to drug development. Financial and regulatory policy significantly impacts the extent and cost of pharmaceutical development, and as such it is important that…

Societal monetary benefits of pharmaceutical innovation: the case of ramipril in Canada.

December 02, 2013

| Thanh Nguyen, Anderson Chuck, Arto Ohinmaa, Philip Jacobs

Objectives: To estimate the monetary benefits of ramipril and its distribution over time among four beneficiaries in Canada: the drug developing manufacturer, generic manufacturers, the healthcare sector and employment sectors.

The impact of the universal infant varicella immunization strategy on Canadian varicella-related hospitalization rates

October 01, 2013

| Arianna Waye, Philip Jacobs, Ben Tan

  INTRODUCTION: Varicella vaccine was introduced to the infant immunization schedule in each province or territory between 2000 and 2007 as a result of the Canadian ImmunizationStrategy. The impact of vaccinating children against this disease is potentially far reaching, asimmunization may also benefit those segments of the population not immunized. The objective of this paper…

Investigation and Analysis of Options to Enhance Canada’s Patented Medicine Price Ceiling Regulatory Regime

October 01, 2013

| Don Husereau, Philip Jacobs

This report is an analysis of the theoretical basis for value-based pricing, relevant international developments, and areas for improvement within Canada’s current patented drug pricing system. This report intends to inform future policy research, advice, and Canadian drug policy discussions regarding the feasibility and implementation of value-based pricing approaches.

Delivery and Evaluation of a Mental health Promotion Intervention for Alberta Workplace Supervisors and Managers

September 01, 2013

| Angus Thompson, Philip Jacobs, Jessica Moffatt, Arianna Waye

This service and evaluation project originated from the Alberta courts via the collaboration of two Alberta Ministries; (1) Alberta Justice & Soliciter General and (2) Alberta Environment and Sustainable Resource Development. The impetus arose when a judge in an environmental protection case observed a need for additional attention to the mental health of workers. An Alberta…

Potential impacts of the Alberta fetal alcohol spectrum disorder service networks on secondary disabilities: a cost-benefit analysis.

July 18, 2013

| Thanh Nguyen, Jessica Moffatt, Philip Jacobs, Anderson Chuck, Egon Jonsson

  Objectives: To estimate the break-even effectiveness of the Alberta Fetal Alcohol Spectrum Disorder (FASD) Service Networks in reducing occurrences of secondary disabilities associated with FASD.

Benefits of pharmaceutical innovation: the case of simvastatin in Canada.

September 19, 2012

| Thanh Nguyen, Anderson Chuck, Arto Ohinmaa, Philip Jacobs

  Background: The benefits of pharmaceutical innovations are widely diffused; they accrue to the healthcare providers, patients, employers, and manufacturers. We estimate the societal monetary benefits of simvastatin in Canada and its distribution among different beneficiaries overtime.

The Distribution of Mental Health Service Costs for Depression in the Alberta Population.

September 10, 2012

| Mel Slomp, Philip Jacobs, Arto Ohinmaa, Roger Bland, Ray Block, Carolyn Dewa, Carina Wang

  OBJECTIVES: In Canada, most mental health services are embedded in the publichealth care system. Little is known of the cost distribution within the mental healthpopulation. Our study aims to estimate the depression care costs of patients with adepression diagnosis, ranking them by the increasing total depression health carecosts.

Changes in drug use are associated with health-related quality of life improvements among methadone maintenance patients with HIV/AIDS.

May 07, 2012

| Bach Tran, Arto Ohinmaa, Anh Duong, Nhan Do, Long Nguyen, Quoc Nguyen, Steve Mills, Philip Jacobs, Stan Houston

  PURPOSE: This longitudinal study assessed the changes in drug use patterns and health-related quality of life (HRQL) among HIV-positive drug users in the first methadonemaintenance treatment (MMT) cohort in Vietnam.

Return on Investment for Mental Health Promotion: Parenting Programs and Early Childhood Development

January 11, 2012

| Carissa Escober-Doran, Philip Jacobs, Carolyn Dewa

This study measures the return on investment for parent training at the pre- or early childhood stage. The purpose is to prevent conduct disorders in childhood, and mental health problems in adolescence and adulthood. The program studied is the Triple P program. The context is a one year birth cohort in Alberta. The costs are for a universal parental training program. The downstream…

Everybody’s business: economic surveillance of public health services in Alberta, Canada

December 13, 2011

| Philip Jacobs, Jessica Moffatt, Arto Ohinmaa, Egon Jonsson

  Background: To address public health risk factors, governments conduct interventions in many different ministries, including non-health ministries. In order to understand the scope and cost of public health in Alberta, we developed a survey of government public health interventions. We included any government ministry or public organization, which includes health as a stated…

The Association of Treatment of Depressive Episodes and Work Productivity.

December 12, 2011

| Carolyn Dewa, Angus Thompson, Philip Jacobs

  OBJECTIVE: About one-third of the annual $51 billion cost of mental illnesses is related toproductivity losses. However, few studies have examined the association of treatment andproductivity. The purpose of our research is to examine the association of depression and itstreatment and work productivity.

Are economic evaluations an important tool in vaccine policy decisions?

October 10, 2011

| Philip Jacobs

  Abstract: In the 1980s, drug prices began rising considerably worldwide, and in the 1990s, countries began incorporating health economics into the scientific review process. Rising prices in vaccines began around the year 2000 and national bodies began to use health economics to review vaccines in the next decade. Health economics is a discipline that evaluates alternative…

Everybody’s Business: The Cost of Multi-Department Involvement in Public Health in Alberta

September 14, 2011

| Philip Jacobs, Jessica Moffatt, Egon Jonsson, Arto Ohinmaa, Cathy Gladwin

The Institute of Health Economics (IHE) has completed a scan to determine what public health-related costs are borne by government departments, ministries, and agencies. The final report, Everybody’s Business: The Cost of Multi-Department Involvement in Public Health in Alberta, was funded by Alberta Health Services (AHS) as part of the Project 2030 initiative that saw the…

The Alberta Survey of Addictive Behaviours and Mental Health in the Workforce: 2009

August 08, 2011

| Angus Thompson, Philip Jacobs, Carolyn Dewa

The Alberta Survey of Addictive Behaviours and Mental Health in the Workforce: 2009 is the third such study conducted since 1992. It provides an interesting, comprehensive picture of many issues related to the mental health of workers across all sectors in Alberta. Introduction IHE is pleased to release the final report of The Alberta Survey of Addictive Behaviours and Mental Health…

Sources of revenue for nonprofit mental health and addictions organizations in Canada.

October 01, 2010

| Carissa Escober-Doran, Philip Jacobs, Carolyn Dewa

  Objective: In Canada charitable or nonprofit organizations provide government-contracted mental health and addictions services, and they augment government funding by raising charitable revenues. This study estimated by source the revenues of nonprofit mental health and addictions organizations in Canada.

Primary Care Economics

September 01, 2010

| Philip Jacobs, Jessica Moffatt, John Rapoport, Neil Bell

This overview provides an analysis of the economic landscape of primary care in Alberta and a discussion of the proposed reforms in terms of ends and means.

Outcomes of the introduction of the MOREOB continuing education program in Alberta.

August 09, 2010

| Thanh Nguyen, Philip Jacobs, Margaret Wanke, Ann Hense, Reg Sauve

  OBJECTIVE: In 2004, the three-module, three-year long patient safety program, Managing Obstetrical Risk Efficiently (MOREOB), was introduced to all clinicians providing obstetrical services in Alberta. We report on an outcomes evaluation of this initiative.

Telehealth in Substance Abuse and Addiction: Review of the Literature on Smoking, Alcohol, Drug Abuse and Gambling

June 01, 2010

| Arto Ohinmaa, Trish Chatterley, Thanh Nguyen, Philip Jacobs

This report reviews the evidence of telehealth in substance abuse and addiction including the literature on smoking, alcohol, drug abuse and gambling. The included telehealth technologies include videoconferencing, computer, Internet, and telephone.

The Cost of Mental Health and Substance Abuse Services in Canada

June 01, 2010

| Philip Jacobs, Carolyn Dewa, Alain Lesage, Helen-Maria Vasiliadis, Carissa Escober-Doran, Gillian Mulvale, Rita Yim

The economic impact of mental illness and addictions is felt throughout society - in the health care system, the social services system, education, criminal justice, and the workplace. In this booklet we conducted a provincial and national level analysis of the expenditures on mental health and addictions in Canada.

Comparative Effectiveness: An Overview

February 13, 2009

| David Hailey, Egon Jonsson, Philip Jacobs

The use of the term “comparative effectiveness” (CE) has attracted considerable attention, particularly in the United States. This booklet examines the concept of CE and its relationship to other assessment frameworks.

Review of Mental Health Economics Evaluation Studies

November 01, 2008

| Arto Ohinmaa, Carolyn Dewa, Trish Chatterley, Philip Jacobs

The mental health economics literature review shows that about one third of the articles found in the search did not include any or just minimal economic information. The database of 4005 references can be used to analyze the mental health economic literature e.g. by diagnosis, type of economic analysis, treatment, publication year, and targeted population.

How Much Should We Spend on Mental Health?

September 04, 2008

| Kim-Lian Lim, Philip Jacobs, Carolyn Dewa

How much should we spend on mental health? provides an overview of the various approaches that have been used to answer the question of health spending, applied to the mental health context. Estimates using several of the approaches are provided. Information Specialists: Trish Chatterley, Liz Dennett

Economics of Childhood Immunizations in Canada: Data Book

May 13, 2007

| Philip Jacobs, Rita Yim, Arto Ohinmaa, Janice Varney, Anita Hanrahan, Joy Loewen, Laura Mashinter, Bev Baptiste, Margaret Russell

This booklet is a compendium of existing statistics related to the economic aspect of childhood immunizations in Canada. It brings together, in one document, data obtained from a wide range of sources. It covers topics related to the economic and epidemiological burden of childhood diseases, resources used, and system performance from provincial, national, and international viewpoints.

Cost-effectiveness in the Detection of Syphilis

February 13, 2007

| Anderson Chuck, Philip Jacobs, Thanh Nguyen, Arto Ohinmaa, Janice Varney

Evaluation of enzyme immunoassay and immunoblot testing for the diagnosis of syphilis in Alberta. A new protocol for testing and diagnosing syphilis has been proposed in Alberta. The protocol proposes replacing rapid plasma reagin (RPR) with enzyme immunoassay (EIA) as the standard initial test and replacing Treponema pallidum (T. pallidum) particle agglutination assay (TPPA) and…

Image-Guided Vacuum-Assisted Breast Biopsy (IGVB) Economic Analysis

June 11, 2006

| Arto Ohinmaa, Egon Jonsson, Philip Jacobs

Institute of Health Economics Working Paper WP 06-02. The purpose of this report is to examine the economic implications for the province if a supplement to the fee schedule were allowed for vacuum-assisted biopsies. NOTE: In 2006 the Alberta Heritage Foundation for Medical Research HTA unit moved to IHE. Documents produced in and prior to 2006 have different formats; the format…

Costing of Alternative Interventions for the Treatment of Morbid Obesity

June 05, 2006

| Philip Jacobs, Arto Ohinmaa, Scott Klarenbach, Anderson Chuck, Raj Padwal, Janice Varney, Doug Lier

Institute of Health Economics Working Paper WP 06-01. The purpose of this report is to examine the economic issues associated with LGB. The following analyses were conducted: a systematic review of the economic literature on obesity-related interventions, with special attention to the differences between gastric bypass and gastric banding; an estimate of the Alberta population…

Health Care Utilization and Direct Health Care Costs of Diabetes in Urban and Rural Saskatchewan

March 17, 2006

| Sheri Pohar, Sumit Majumdar, Philip Jacobs, Jeffrey Johnson

Institute of Health Economics Working Paper WP 06-04. The purpose of this analysis was to compare health care utilization as well as costs and mortality of individuals with diabetes in the province of Saskatchewan from 1999 to 2001, according to residential location. NOTE: In 2006 the Alberta Heritage Foundation for Medical Research HTA unit moved to IHE. Documents produced in…

Epidemiologic and Cost Trends in Diabetes in Saskatchewan, 1991 To 2001

October 01, 2005

| Sheri Pohar, Scot Simpson, Sumit Majumdar, Philip Jacobs, Arto Ohinmaa, William Osei, Mary Rose Stang, Winanne Downey, Jeffrey Johnson

Institute of Health Economics Working Paper WP 05-06. The purpose of this study was to analyze epidemiologic and cost trends from 1991 to 2001 in the province of Saskatchewan for a cohort of individuals identified as having diabetes and for a randomly selected control cohort. The objectives were to: explore epidemiologic trends (i.e., prevalence, incidence and mortality) in diabetes…

Cost Estimation of Point of Care B-Type Natriuretic Peptide for the Diagnosis of Heart Failure in the Emergency Department - Application to Alberta

May 30, 2005

| Anderson Chuck, Philip Jacobs

Alberta Heritage Foundation for Medical Research (AHFMR) Information Paper #25. The aim of this report is to provide a cost estimate, over a one year time period from a payer’s perspective, of Biosite Triage Point-of-Care (POC) B-Type Natriuretic Peptide (BNP) assay used to rule out congestive heart failure (CHF) from other pulmonary conditions for patients presenting in…

Allogeneic stem cell transplantation methods

January 01, 2000

| Philip Jacobs, David Hailey, Nadine MacLean

Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #18. This report has been prepared following interest by the Alberta Cord Blood Bank in obtaining advice on the comparative effectiveness and costs of different types of stem cell transplantation. Earlier assessments by the Foundation have considered peripheral blood stem cell transplantation and cord blood transplantation.…

An assessment of routine telepsychiatry services

November 01, 1999

| Jennifer Simpson, Sandra Doze, Douglas Urness, David Hailey, Philip Jacobs

Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #20. This report presents data from the telepsychiatry program subsequent to the pilot project. The assessment of telepsychiatry beyond the pilot project stage had two primary focuses: a) to develop and document information collection systems initiated during the pilot project evaluation, and b) to assess the operation…

Cord Blood Transplantation

December 15, 1998

| Maureen Yunkap Kwankam, David Hailey, Philip Jacobs

Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #13. This assessment has been prepared in view of the interest at the University of Alberta Hospital in developing a cord blood banking facility in the province and to provide information to decision makers on the current status of cord blood transplantation (CBT). The principal purpose of the assessment was to…

Assessment of telehealth applications - Version 1

October 01, 1997

| David Hailey, Philip Jacobs

Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #4. This outline of issues in the assessment of telehealth is intended as a resource document for health care funders, providers and administrators. Health authorities and others in Alberta face decisions on the procurement and use of this information and communication technology. Such decisions should be informed…

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